Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Iron catalysis (2)
- Aggregation-induced emission (AIE)aggregation-caused quenching (ACQ)germacyclopentadienes (1)
- Amyloid-beta (1)
- Biommimetic oxidation chemistry (1)
- Carbohydrates (1)
-
- Charge transfer (1)
- Chemical Glycosylation (1)
- Coordination (1)
- Crystallography (1)
- Germafluorenes (1)
- Germanium fluorescein (1)
- Germolephotoluminescencesolid-state luminescence (1)
- Glycosyl thiocarbamates (1)
- Iron (1)
- Iron indenyl complexes (1)
- Mechanism (1)
- Metal cations (1)
- Microglia (1)
- Mukaiyama aldol reactions (1)
- Organometallic chemistry (1)
- Organometallic complexes (1)
- Oxidation chemistry (1)
- Protofibrils (1)
- Siloles (1)
- Synthesis (1)
Articles 1 - 6 of 6
Full-Text Articles in Physical Sciences and Mathematics
Glycosyl Thiocarbamates As New Building Blocks For Chemical Glycosylation, Sneha Chandrashekhar Ranade
Glycosyl Thiocarbamates As New Building Blocks For Chemical Glycosylation, Sneha Chandrashekhar Ranade
Dissertations
Having multiple functions in biological systems e.g. fertilization, blood group determination, cell growth; carbohydrates have remained attractive subjects for the study. They are also involved in various life threatening biological processes, such as viral and bacterial infections, tumor development, etc. Understanding of these involvements/interactions of carbohydrates in such critical processes is essential for the development of carbohydrate based vaccines and therapeutics. Although carbohydrates are present abundantly in nature, their isolation is cumbersome and low yielding, which is why, the synthesis of carbohydrate units has been of interest to many scientists. Efforts have been made to make these synthetic methods more …
Application Of Iron Complexes As Catalysts In C-O And C-C Bond Forming Reactions, Pushkar Sudhakar Shejwalkar
Application Of Iron Complexes As Catalysts In C-O And C-C Bond Forming Reactions, Pushkar Sudhakar Shejwalkar
Dissertations
‘Green Chemistry’ is a philosophy that encourages chemists in research and industry to reduce toxic waste for cleaner and safer chemical production. Oxidation reactions are commonly used in industry and are traditionally achieved by methods that involve toxic metals (such as chromium) and solvents, generating considerable waste compared to the value of the final product. The Mukaiyama Aldol reaction is another organic reaction that utilizes metals as Lewis acid catalysts. The principles of Green Chemistry suggest that chemical reactions should be performed with a maximum of efficiency and with a minimum of side product formation, accompanied by a minimal use …
Siloles Bearing Coordination-Active 2,5-Substituents: Synthesis, Reactivity, Structural And Spectral Properties., James Bryan Carroll
Siloles Bearing Coordination-Active 2,5-Substituents: Synthesis, Reactivity, Structural And Spectral Properties., James Bryan Carroll
Dissertations
Siloles, or silacyclopentadienes and other group 14 metalloles are structurally analogous to their all-carbon analogue, cyclopentadiene, except for the heavy group 14 element (i.e., Si, Ge, Sn, and Pb) in the 1-position. The placement of the heavy element in this position allows for unique properties, such as high electron affinity, mobility, and bathochromically shifted optical spectra, as compared to cyclopentadienes, and the relatively low-lying lowest-unoccupied molecular orbital (LUMO) helps to account for these properties. The substituents about the silole have a significant impact on the electronics and properties observed, with 2,5-substituents inducing the most substantive changes. Even as many 2,5-substituents …
The Investigation Of Iron(Ii) Complexes And Their Catalytic Applications, Matthew Joseph Lenze
The Investigation Of Iron(Ii) Complexes And Their Catalytic Applications, Matthew Joseph Lenze
Dissertations
Several new η5-indenyl (Ind) complexes of iron featuring phosphinooxazoline (PHOX) ligands were synthesized and spectroscopically characterized and in a few cases structurally. The complexes were synthesized using phosphinooxazoline ligands and the corresponding iron precursor [Fe(η5-Ind) I(CO)2], yielding novel piano-stool iron complexes of the general formula [Fe(η5-Ind)(CO)(PHOX)]+ in 73% to 81% isolated yields. The complexes were tested for their efficacy in a carbon-carbon bond formation known as the Mukaiyama aldol reaction. The [Fe(η5-Ind)(CO)(PHOX)]+ complexes were capable of activating the carbonyl of aromatic aldehydes towards by attack 1-(tertbutyldimethylsilyloxy)-1-methoxyethene to form the expected silyl protected β-hydroxyesters. In these complexes, the η5-η3 haptotropic shift …
Synthesis And Characterization Of Luminescent Cyclic Germanium Compounds, Teresa Lynn Bandrowsky
Synthesis And Characterization Of Luminescent Cyclic Germanium Compounds, Teresa Lynn Bandrowsky
Dissertations
The vision in the field of organic electronics is the realization of flexible, easily manufactured, low cost optoelectronics for use in organic light emitting diodes (OLEDs) for large area displays and lighting applications, organic photovoltaic cells, and organic field-effect transistors. The active layers within such devices are composed of semiconducting small molecules or polymers. The rich chemistry of new π-conjugated materials holds the key to continued progress by allowing the material properties of organic semiconductors to be readily tuned towards application specific demands. At the core of this subject matter is how to modify the electronic structures of π-conjugated molecules …
Microglial Activation By Amyloid-Beta, Geeta Subhash Paranjape
Microglial Activation By Amyloid-Beta, Geeta Subhash Paranjape
Dissertations
Paranjape, Geeta S.,Ph.D.,University of Missouri-Saint Louis, May 2012. Aβ(1-42) Protofibrils But Not Fibrils Activate Microglia. Major Professor: Michael R. Nichols. One of the hallmark features of the Alzheimer’s disease (AD) brain is the extracellular deposition of amyloid-β protein (Aβ) in both fibrillar (senile plaques) and diffuse forms. Significant proinflammatory markers including activated microglia and cytokines have been detected surrounding the plaques but are absent in diffuse areas suggesting that microglial activation is sensitive to Aβ structure. Since Aβ displays structural polymorphism in vitro, we sought to determine the relationship between Aβ aggregation state and microglial proinflammatory response. Size exclusion chromatography …