Physical Sciences and Mathematics Commons^™

Engineering Nanoparticles Surface For Biosensing: "Chemical Noses" To Detect And Identify Proteins, Bacteria And Cancerous Cells, Oscar Ramon Miranda-Sanchez

Open Access Dissertations

Rapid and sensitive detection of biomolecules is an important issue in nanomedicine. Many disorders are manifested by changes in protein levels of serum and other biofluids. Rapid and effective differentiation between normal and cancerous cells is an important challenge for the diagnosis and treatment of tumor. Likewise, rapid and effective identification of pathogens is a key target in both biomedical and environmental monitoring. Most biological recognition processes occur via specific interactions. Gold nanoparticles (AuNPs) feature sizes commensurate with biomacromolecules, coupled with useful physical and optical properties. A key issue in the use of nanomaterials is controlling the interfacial interactions of …