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Full-Text Articles in Physical Sciences and Mathematics
Nanomaterials For Double-Stranded Rna Delivery, Stuart Lichtenberg
Nanomaterials For Double-Stranded Rna Delivery, Stuart Lichtenberg
Theses and Dissertations--Plant and Soil Sciences
RNA interference has enormous potential as a potent, specific, and environmentally friendly alternative to small molecule pesticides for crop protection. The use of exogenous double-stranded RNA offers flexibility in targeting and use in crops in which transgenic manipulation is not an option. The combination of RNAi with nanotechnology offers further advantages that are not available with dsRNA alone. In this work, I have evaluated several different combinations of nanomaterials and polymers for use in RNAi-based pest control systems. First, I have characterized the use of chitosan/dsRNA polyplex nanoparticles for gene knockdown using the model nematode Caenorhabditis elegans. Though chitosan/dsRNA …
Transformations, Bioavailability And Toxicity Of Manufactured Zno Nanomaterials In Wastewter, Sewwandi Rathnayake
Transformations, Bioavailability And Toxicity Of Manufactured Zno Nanomaterials In Wastewter, Sewwandi Rathnayake
Theses and Dissertations--Plant and Soil Sciences
In order to properly evaluate the ecological and human health risks of ZnO Manufactured nanomaterials (MNMs) released to the environment, it is critical to understand the likely transformation products in the wastewater treatment process and in soils receiving biosolids. To address this critical knowledge gap, we examined the transformation reactions of 30 nm ZnO MNMs in single component and multi-component systems, with phosphate and natural organic matter (NOM). We also assessed the influence of nano ZnO transformation on the bioavailability, and toxicity of ZnO transformation products to Triticum aestivum. The data revealed that ZnO MNMs react with phosphate at …