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Full-Text Articles in Physical Sciences and Mathematics
Low Voltage Electrowetting Device And Method For Making Same, Yuguang Cai, Xiaoning Zhang
Low Voltage Electrowetting Device And Method For Making Same, Yuguang Cai, Xiaoning Zhang
Chemistry Faculty Patents
An electrowetting device includes a substrate having a first face, a charged adhesion layer immobilized on the first face of the substrate and a dielectric layer bound to the charged adhesion layer. An unbound ionic liquid phase contacts the dielectric layer.
Trans-Excision-Splicing Ribozyme And Methods Of Use, Stephen M. Testa, Michael A. Bell
Trans-Excision-Splicing Ribozyme And Methods Of Use, Stephen M. Testa, Michael A. Bell
Chemistry Faculty Patents
A group I intron-derived ribozyme which binds RNA in trans, excises an internal segment from within the RNA, and splices the remaining 5′ and 3′ ends of the RNA back together (the trans-excision-splicing reaction) is disclosed. The excised segment can be as long as 28 nucleotides, or more, and as little as one nucleotide. The ribozymes of the invention are easily modified to alter their sequence specificity. Such ribozymes represent a new and potentially powerful class of generally adaptable genetic therapeutics.
Methods And Kit For Determination Of Prostacyclin In Plasma, Sylvia Daunert, Michael Poon, Urvee Desai, Sapna K. Deo
Methods And Kit For Determination Of Prostacyclin In Plasma, Sylvia Daunert, Michael Poon, Urvee Desai, Sapna K. Deo
Chemistry Faculty Patents
A solid-phase immunoassay for 6-keto-Prostaglandin F1α, the stable hydrolysis product of prostacyclin (Prostaglandin I2) is disclosed. Prostacyclin, a potent vasodilator with anti-platelet and anti-proliferative properties is an effective treatment for primary pulmonary hypertension and pulmonary arterial hypertension associated with scleroderma and scleroderma-like syndrome. Levels of 6-keto-Prostaglandin F1α can be directly correlated with levels of prostacyclin. Therefore, 6-keto-Prostaglandin F1α has become the indicator of choice to measure prostacyclin levels. The single step immunoassay for 6-keto-Prostaglandin F1α uses the bioluminescent protein, aequorin as a label. Analyte-label conjugates were constructed by linking the carboxyl group of …
Trans-Excision-Splicing Ribozyme And Methods Of Use, Stephen M. Testa, Michael A. Bell
Trans-Excision-Splicing Ribozyme And Methods Of Use, Stephen M. Testa, Michael A. Bell
Chemistry Faculty Patents
A group I intron-derived ribozyme which binds RNA in trans, excises an internal segment from within the RNA, and splices the remaining 5′ and 3′ ends of the RNA back together (the trans-excision-splicing reaction) is disclosed. The excised segment can be as long as 28 nucleotides, or more, and as little as one nucleotide. The ribozymes of the invention are easily modified to alter their sequence specificity. Such ribozymes represent a new and potentially powerful class of generally adaptable genetic therapeutics.
Dual Stage Microvalue And Method Of Use, Marc J. Madou, Sylvia Daunert
Dual Stage Microvalue And Method Of Use, Marc J. Madou, Sylvia Daunert
Chemistry Faculty Patents
A micro-machined drug delivery device and method of use for the delivery of labile drugs is disclosed. A micro-machined sensing device and method of use is also disclosed. A micro-machined drug delivery and sensing device and method of use is additionally disclosed. All three devices are intended to be inserted into a patient's body. The drug delivery devices allow for the mixing of drug components prior to the release of the mixture into the patient's body where the mixture is labile. The micro-machined sensing device is suitable for monitoring the concentration of a specific chemical in a patient's body fluids …
Method Of Solubilizing Single-Walled Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Jian Chen
Method Of Solubilizing Single-Walled Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Jian Chen
Chemistry Faculty Patents
Naked single-walled nanotube carbon metals and semiconductors are dissolved in various organic solutions.
Method Of Solubilizing Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Mark A. Hamon
Method Of Solubilizing Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Mark A. Hamon
Chemistry Faculty Patents
Carbon nanotubes are dissolved in organic solutions by attaching an aliphatic carbon chain (which may contain aromatic residues) so as to render the carbon nanotubes soluble.
Method Of Solubilizing Unshortened Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Jian Chen, Mark A. Hamon
Method Of Solubilizing Unshortened Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Jian Chen, Mark A. Hamon
Chemistry Faculty Patents
Naked carbon nanotubes are dissolved in organic solutions by terminating the nanotubes with carboxylic acid groups and attaching an aliphatic carbon chain so as to render the carbon nanotubes soluble.
Method Of Solubilizing Shortened Single-Walled Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Jian Chen
Method Of Solubilizing Shortened Single-Walled Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Jian Chen
Chemistry Faculty Patents
Naked single-walled nanotube carbon metals and semiconductors were dissolved in organic solutions by derivatization with SOCl2 and octadecylamine charge. Both ionic (charge transfer) and covalent solution phase chemistry with concomitant modulation of the single-walled carbon nanotubes (SWNT) band structure were demonstrated. Solution phase near-IR spectroscopy was used to study the effects of chemical modifications on the band gaps of the SWNTs. Reaction of solubilized SWNTs with dichlorocarbene led to functionalization of the nanotube walls.