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Part I : Isolation Of Dipentyl 2-(4-(Pentan-3-Yl) Phenyl) Malonate From Sanguisorba Officinalis Labill Part Ii: Synthesis Of A Novel Family Of Ethers Of Podocarpic Acid, Manjeera Yalavarty

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The goal of part I of this thesis was to isolate pure anti cancer compounds from the Russian plant Sanguisorba officinalis. This plant was selected for investigation because it showed 100% activity against leukemia (L1210 mouse leukemia cells) during the preliminary screening of approximately 100 Russian plant extracts. This work has resulted in the isolation of novel compound 11 using traditional chromatography techniques. Compound 11 was characterized with spectroscopic techniques such as IR, 1H NMR, 13C NMR, DEPT, DQCOSY and MS. Compound 11 was assigned the structure dipentyl 2-(4-(pentan-3-yl) phenyl) malonate. The goal of part II of this thesis was …