Physical Sciences and Mathematics Commons^™

Multi-Dimensional Mass Spectrometry For The Characterization Of Glycopolymers, Maria Ganios

Williams Honors College, Honors Research Projects

Several glycopolymers synthesized by Activators regenerated by electron transfer atom transfer radical polymerization (ARGET ATRP), were characterized by mass spectrometry to elucidate their microstructure and architecture. Analyses were performed using Matrix Assisted Laser Desorption Ionization- Time of Flight/ Time of Flight (MALDI-ToF/ToF) and Electrospray Ionization Mass Spectrometry (ESI-MS) instruments. The linear isopropylidenated glycopolymer (P65B1) analyzed with ESI-MS also was examined with multi-stage mass spectrometry (MSⁿ) using collision induced dissociation (CID) to examine the tetramer parent ion. This glycopolymer was found to be either cyclic or linear (sans end groups) due to the data being fit for both forms …