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Determination Of The Structure Of Sphingomyelin By Tandem Mass Spectrometry And Matrix - Assisted Laser Desorption/Ionization, Antonio Ganios
Determination Of The Structure Of Sphingomyelin By Tandem Mass Spectrometry And Matrix - Assisted Laser Desorption/Ionization, Antonio Ganios
Williams Honors College, Honors Research Projects
Mass spectrometry is a method that uses masses to determine the structure of a compound. This is completed by first charging the compound until it is a cation or anion, and then its molecular weight can be determined by measuring a mass to charge ratio. The focus of this study was determination of sphingomyelin’s structure. The purpose of this was that sphingomyelin has been shown to play a critical role in many biological pathways and being able to identify this lipid could prove to be beneficial for preventative medicine. Utilizing electrospray ionization (ESI) Quadruple-Time-of-flight (Q-TOF) mass spectrometry on a Waters …