Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Physical Sciences and Mathematics
Cerimetric Determination Of Propranolol In Bulk Drug Form And In Tablets, Kanakapura Basavaiah, Umakanthappa Chandrashekar, H. Chandrashekar Prameela
Cerimetric Determination Of Propranolol In Bulk Drug Form And In Tablets, Kanakapura Basavaiah, Umakanthappa Chandrashekar, H. Chandrashekar Prameela
Turkish Journal of Chemistry
Two simple, accurate and precise methods are described for the determination of propranolol hydrochloride with cerium(IV) sulphate. The titrimetric method is based on the oxidation of the drug by a known excess amount of cerium(IV) sulphate and back titration of the unconsumed oxidant with ammonium ferrous sulphate. In the spectrophotometric method, the unreacted cerium(IV) sulphate is treated with iron(II) sulphate, and the iron(III) sulphate produced is complexed with thiocyanate and measured at 480 nm, thereby permitting the determination of the amount of unreacted cerium(IV) sulphate. In both procedures, the amount of the reacted oxidant corresponds to the drug content. Different …
Application Of Potassium Chromate-Diphenylcarbazide In The Quantitative Determination Of Ascorbic Acid By Spectrophotometry, Meissam Noroozifar, M. Khorasani Motlagh
Application Of Potassium Chromate-Diphenylcarbazide In The Quantitative Determination Of Ascorbic Acid By Spectrophotometry, Meissam Noroozifar, M. Khorasani Motlagh
Turkish Journal of Chemistry
A spectrophotometric procedure for the determination of ascorbic acid in pure form and in a number of pharmaceutical preparations and real samples has been developed that offers the advantages of simplicity, accuracy, precision and sensitivity over many other methods. The method is based on the oxidation of ascorbic acid by a known excess amount of potassium chromate followed by the estimation of the unreacted amount of chromate by reactions with sym-diphenylcarbazide. The reacted oxidant corresponds to the ascorbic content. At the maximum absorption of 548 nm, Beer's law is obeyed up to 5 \mu g/mL of ascorbic acid. Statistical treatment …
Atomic Absorption And Spectrophotometeric Determinations Of Salicylhydroxamic Acid In Its Pure And Pharmaceutical Dosage Forms, Alaaeldin Abdelaziz Salem, Mohamed Mohamed Omar
Atomic Absorption And Spectrophotometeric Determinations Of Salicylhydroxamic Acid In Its Pure And Pharmaceutical Dosage Forms, Alaaeldin Abdelaziz Salem, Mohamed Mohamed Omar
Turkish Journal of Chemistry
A new method for the indirect determination of salicylhydroxamic acid (SHAM) using atomic absorption spectrometry (AAS) was proposed. The method is based on precipitating the ion associate complex of SHAM with [Cu (NH_{3})_{4}]^{2+}. The excess, unreacted, Cu^{2+} ions were determined using AAS. Another spectrophotometric method based on measuring the absorbance of the formed [Cu (NH_{3})_{4}]-SHAM complex in dioxane was proposed. The green color of the complex formed was measured at 330 nm. The two methods were successfully used for determining SHAM in its pure and pharmaceutical dosage forms. Using AAS, the drug was determined over a concentration range of 3.06 …