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Full-Text Articles in Physical Sciences and Mathematics
Synthetic Methodologies Using Nucleophile-Electrophile Chemistry, Jacob C. Hood
Synthetic Methodologies Using Nucleophile-Electrophile Chemistry, Jacob C. Hood
Graduate Research Theses & Dissertations
Synthetic organic chemistry is a vital part of the modern world – making up 15-20% of the U.S. economy. New synthetic reactions can lower manufacturing costs and create more environmentally friendly processes. Substitution, addition, and superelectrophilic chemistry are potent tools to afford potentially essential compounds. The work outlined in this dissertation recounts the expansion of synthetic methodologies employing substrates with a wide range of electrophilicities toward synthesizing heterocyclic molecules. These concepts are summarized in chapter 1. Chapter 2: N-Heterocyclic alcohols are excellent substrates for superacid-promoted Friedel-Crafts reactions. The N-heterocyclic alcohol ionizes to produce reactive, dicationic intermediates, providing good to excellent …
The Chemistry Of Superelectrophilic Phosphonium Ions, Nathan David Scanlon
The Chemistry Of Superelectrophilic Phosphonium Ions, Nathan David Scanlon
Graduate Research Theses & Dissertations
A series of aryl-substituted phosphines have been prepared using superelectrophilic aromatic substitution chemistry. This chemistry involves reactive phosphonium-carbenium dications and related species. In addition to low molecular weight aryl-substituted phosphines, we also are able to prepare functionalized polystyrene products.