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Cofactor Control Of A Vital Enzymatic Reaction;The Effect Of Factor Va On Thrombin Formation During Blood Coagulation, Jamila Hirbawi
Cofactor Control Of A Vital Enzymatic Reaction;The Effect Of Factor Va On Thrombin Formation During Blood Coagulation, Jamila Hirbawi
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The LONG-TERM goal of our research is to study and analyze the structure and function of the factor V molecule in order to understand its regulatory effects on the natural process of hemostasis and its role in the life-threatening development of deep venous thrombosis. The SHORT-TERM goal of our research is to identify the amino acid residue(s) of factor V that interact with prothrombin during the assembly and function of the prothrombinase complex in order to fully understand its particular role in maintaining the integrity of the blood coagulation cascade. The final goal of the coagulation cascade is the formation …