Physical Sciences and Mathematics Commons^™

Detection Of Alzheimer's Disease And Other Diseases Using An Improved Photoaffinity Labeling Method, Boyd E. Haley

Chemistry Faculty Patents

A method for diagnosing a neurological disease comprising detecting a neurological disease-specific biochemical marker macromolecule within a sample of extracted cerebral spinal fluid is disclosed. In particular, a radioactively labeled photoaffinity probe is used to diagnose a neurological disease. For instance, Alzheimer's disease can be diagnosed by detecting a disease-specific protein having a molecular weight of about 42,000 daltons, i.e., glutamine synthetase.

Atmospheric Hydrocarbon Analysis, Dawei Han

Dissertations and Theses

This treatise studied two correlated important issues in atmospheric chemistry: real-time monitoring of ambient air and removal mechanisms of atmospheric hydrocarbons. An analytical system was designed for the purpose of identification and measurement of sub-ppb level hydrocarbons of different reactivities in air samples. This analytical system was then applied to a series of smog-chamber studies which simulated the removal of reactive hydrocarbons from the atmosphere by reaction with hydroxyl radicals. Six representative atmospheric hydrocarbons (hexane, octane, toluene, m-xylene, a-xylene and mesitylene) were selected for these experiments. The experimental data indicated that the decay of atmospheric hydrocarbons under laboratory conditions is …

Polymer Science At The Kyoto Institute Of Technology, Kyoto, Japan, Otto Vogl, Shinzo Kohjiya, Takeo Araki

Emeritus Faculty Author Gallery

No abstract provided.

Advances In Degradable Polymers, Otto Vogl, Andrea Eckert

Emeritus Faculty Author Gallery

No abstract provided.

66. In Memoriam Herman F. Mark, Otto Vogl, Marcel Dekker

Emeritus Faculty Author Gallery

No abstract provided.

A Characterization Of Extractable, Hydroxylated Fatty Acid Bearing Components In Legionella Pneumophila, Jonathan R. Lane

Electronic Theses and Dissertations

Extraction of the lipids of Legionella pneumophila yields phases unlike those produced from other Gram-negative bacteria. A viscous interface forms between the aqueous (wash) and organic phases. More than half of the hydroxylated fatty acids were found distributed between the aqueous phase and the interfacial material, fractions in which such constituents have not been reported in other Gram-negative species. It was further observed that after the material from the aqueous/interfacial phase was dissolved in methanol or chloroform/methanol (2:1 (V/V)), the addition of acetone would create a white, flocculent precipitate. Analyses showed that the supernatant contained fatty acids that were nonhydroxylated …

Polymer Science At The Kyoto Institute Of Technology, Kyoto, Japan, Otto Vogl, Shinzo Kohjiya, Takeo Araki

Otto Vogl

No abstract provided.

66. In Memoriam Herman F. Mark, Otto Vogl, Marcel Dekker

Otto Vogl

No abstract provided.

Advances In Degradable Polymers, Otto Vogl, Andrea Eckert

Otto Vogl

No abstract provided.

Neutron-Diffraction And Mössbauer-Effect Studies Of Pr₂(Fe₁₋ₓmnₓ)₁₄B, Oran Allan Pringle, Jie Fu, Gary J. Long, William Joseph James, Decai Xie, William B. Yelon, Fernande Grandjean

Physics Faculty Research & Creative Works

A neutron-diffraction investigation of a series of Pr₂(Fe _1-xMn_x)₁₄B samples, with x values of 0.00, 0.11, 0.22, 0.30, and 0.35, reveals a preference for the manganese to occupy the 8j₂ transition-metal site,the transition-metal site with the largest Wigner-Seitz cell volume. Similar site occupancies have been reported previously for Er₂(Fe_1-xMn_x) ₁₄B and Y₂(Fe_1-xMn_x) ₁₄B. An analysis of the 295-K Mössbauer spectrum of Pr₂(Fe_0.89Mn_0.11)₁₄B indicates that the internal hyperfine fields on the …

Thermodynamic Properties Of Mixtures Of Aqueous Solutions Of Hydrochloric Acid And Cadmium Chloride, Copper Chloride, Manganese Chloride, And Zinc Chloride, Samia A. Kosa

Masters Theses

The densities of mixtures of aqueous solutions of hydrochloric acid and cadmium chloride, copper chloride, manganese chloride, and zinc chloride have been measured at constant ionic strengths of 1.0 and 3.0 molal at 25 °C. In the case of HCl, CdCl₂ , and ZnCl₂ the literature data were refit using Pitzer' s apparent molal volume equation and the binary solution parameters were determined. Density data were used to determine the volume of mixing (∆V_m). Data from Torok and Berecs were combined with our data for the mixtures with CuCl₂ and MnCl₂. Pitzer's volume …

Separation Of Copper And Iron In Natural Waters By Solid-Phase Extraction, Charles Bui

Masters Theses

A separation scheme has been developed by utilizing Solid-Phase Extraction cartridges in order to isolate and characterize the charge of metals and their complexes in natural waters. These species can be analyzed by Atomic Absorption Spectroscopy (AAS), Inductively Coupled Plasma (ICP), and Ultraviolet-Visible Spectrophotometry (UVVIS).

This separation scheme would permit the determination of the concentration of metals, as well as providing information about the forms in which the metals exist, e.g., charge of metallic complexes.

Synthetic metal complexes were prepared in the laboratory in order to study the separation scheme as well as trying to understand the binding stability of …

Senior Theses: Department Of Physical Sciences, Frank Baldridge, Billy B. Stapleton, James Bond, Mark A. Blair

Morehead State Theses and Dissertations

1993 Fall Semester Senior Theses for the class Physical Science 471:

Petrologic Classification of Igneous and Metamorphic Rocks by Frank Baldridge

X -Ray Analysis of Cave Sediments From Pigeon Water Cave of Northeastern Pine Mountain by Billy B. Stapleton

The Correlation of Stream-deposited Breccias In Bat Cave, Carter Caves, Kentucky by James Bond

Jointing and Faulting in Selected Areas of Eastern Kentucky by Mark A. Blair

Coal Sulfur Forms Determination Using Thermal Analysis Methods, Bucheng Wang

Masters Theses & Specialist Projects

By optimizing parameters including temperature, reaction time, reagent concentration and pressure, the optimum conditions for the mild oxydesulfurization of coals were determined to be 150°C-200"C and 10 atmospheres oxygen in aqueous slurries of coal reacted with 1 M NH₄OH for 1.5-2 hours. The total amount of sulfur removed from -60 mesh coals ranges from 51% to 78% with a mean of 64%, while the amount of inorganic sulfur removed from the coals ranged from 66% to 91% with a mean of 77%. The amount of organic sulfur removed from the samples ranged from 36% to 50% with a …

Monte Carlo Simulation Of The Solid To Super Liquid Phase Transition Of Langmuir Monolayers Using Cross-Section Potentials, D.R. Swanson, Robert J. Hardy, Craig J. Eckhardt

Craig J. Eckhardt Publications

A cross-section potential which models the interaction of two planar objects of prescribed shape is developed and used to model the interactions of amphiphiles in vertical phases of Langmuir monolayers. The results of Monte Carlo simulations of an isobaric-isothermal ensemble show qualitative agreement with experiment. The model system undergoes a continuous, bound-to-free rotator transition between phases of the same symmetries as the solid (S) and super liquid (LS) phases exhibited by fatty acid films.

Polymer Science In Milano - Italy, Otto Vogl, Lido Porri, Mario Farina, Guido Audisio

Emeritus Faculty Author Gallery

No abstract provided.

Iupac Symposium On Ring Opening Polymerization '92, Warsaw, Poland, July 7-11, 1992, Otto Vogl, Zbigniew Florjanczyk

Emeritus Faculty Author Gallery

No abstract provided.

67. In Memoriam Hermann F. Mark, Otto Vogl

Emeritus Faculty Author Gallery

No abstract provided.

Piezomodulated-Raman-Spectroscopy Study Of The Phase Transition In Phenothiazine, J. Sartwell, Craig J. Eckhardt

Craig J. Eckhardt Publications

Single crystals of phenothiazine undergo a displacive order-disorder phase transition near 250 K. The microscopic mechanism of this transition is not clear owing to the complexity of a disordered lattice and the lack of direct mode-anharmonicity data. Unstable optical modes have been observed in phenothiazine and are regarded as coupled, by symmetry, to an acoustic mode that becomes overdamped through the phase transition. The latter is considered to have the primary role in the phase transition. This premise is in doubt, however, based on the optical-mode anharmonicity directly observed by uniaxial-piezomodulation-Raman-spectroscopy results presented here. Anharmonic responses are observed in the …

67. In Memoriam Hermann F. Mark, Otto Vogl

Otto Vogl

No abstract provided.

Polymer Science In Milano - Italy, Otto Vogl, Lido Porri, Mario Farina, Guido Audisio

Otto Vogl

No abstract provided.

Iupac Symposium On Ring Opening Polymerization '92, Warsaw, Poland, July 7-11, 1992, Otto Vogl, Zbigniew Florjanczyk

Otto Vogl

No abstract provided.

Brillouin-Scattering Study Of The Elastic Constants Of Phenothiazine Through The Phase Transition, J. Sartwell, Craig J. Eckhardt

Craig J. Eckhardt Publications

It has been proposed that single crystals of phenothiazine undergo a proper ferroelastic phase transition: Pnma(D_2h)→P2₁/c (C_2h). This premise is in conflict with Brillouin-scattering studies from both quasi- and high-symmetry longitudinal and transverse acoustic modes reported here. The C₅₅ elastic constant of phenothiazine as an orthorhombic crystal at ambient conditions shows no temperature dependence. The inelastic, light-scattering spectra support an order-disorder phase transition; no significantly unstable acoustic phonons were observed through the phase transition. Laser diffraction from structural domains reveals that the crystal is polysynthetically …

Neutron-Diffraction And Mössbauer Effect Study Of The Preferential Silicon Site Occupation And Magnetic Structure Of Nd₂Fe₁₄₋ₓsiₓb, Gaya Kanishka Marasinghe, Oran Allan Pringle, Gary J. Long, William Joseph James, Dianne J. Xiao, J. L. Li, William B. Yelon, Fernande Grandjean

Physics Faculty Research & Creative Works

A neutron-diffraction study of Nd₂Fe_14-xSi_xB has shown that silicon preferentially occupies the 4c site in the transition-metal sublattice in Nd₂Fe₁₄B. Silicon also exhibits a moderate preference for the 8j₁ site, is almost excluded from the 16k₂ site, and avoids the 16k₁, 8j₂, and 4e sites. The silicon site occupancy is correlated with a preference for a silicon atom to have rare-earth atoms in its coordination environment. The Mössbauer spectra of Nd₂Fe_14-xSi_xB have been fit with a model which …

The Development Of New Methods For Coal Sulfer Forms & Sulfur In Ash Determination, Robert Forsythe

Masters Theses & Specialist Projects

The development of new procedures to determine the amount and/or types of sulfur in coal and coal products is an ongoing process for coal scientists This development is driven by the problems and inconveniences of the current ASTM methods In this thesis, the work done at Western Kentucky University in the development of two new sulfur determination procedures will be described. The first procedure can be used as an alternative method for coal sulfur forms analysis with results comparable to the ASTM method. This procedure involves heating the coal samples at 365°C and 440°C for thirty minutes to selectively remove …

Nitric Oxide Absorption From Flue Gas With Cumene Hydroperoxide Solution, Chung-Der Chen

Theses

The absorption of nitric oxide from gas streams with cumene hydroperoxide (CHP) in n-hexadecane (cetane) as the scrubbing solution was investigated. The efficiency of the scrubbing solution to remove nitric oxide was evaluated over the temperature range of 90 to 110°C, concentration range of 0.1 to 0.5M, and residence time of 12 to 80 seconds. The products were analyzed by gas chromatography (GC), Fourier transform infrared spectroscopy (FTIR), and ion chromatography (IC). The goal of this research was to determine the NO removing efficiency of cumene hydroperoxide solution, a relatively inexpensive tertiary organic hydroperoxide. Also, a possible reaction mechanism for …

Interaction Of Cationic Porphyrins With Dna, Ulrica Sehlstedt, Pamela Carter, Jerry Goodisman, James C. Dabrowiak, Seog K. Kim

Chemistry - All Scholarship

Utilizing linear dichroism (LD), circular dichroism (CD), and fluorescence energy transfer, the binding geometries of a series of Co3+-porphyrins and their free ligands were examined. The compounds studied were Co-meso-tetrakis(N-methylpyridinium-4-yl)porphyi(nC oTMPyP) and its free ligand (H2- TMPyP), Co-meso-tetrakis(N-n-butylpyridinium-4-yl)porphyrin( CoTBPyP) and its free ligand (H2TBPyP), and Co-meso-tetrakis(N-n-octylpyridinium-4-yl)porphyrin (CoTOPyP). The two non-metalloporphyrins exhibit negative LD, having angles of roughly 75' relative to the DNA helix axis. They also display negative CD and a significant contact energy transfer from the DNA bases. On the other hand, the three metalloporphyrins display orientation angles of roughly 45' between the porphyrin plane and the helix axis …

Purification And Characterization Of A Gamma-Like Dna-Polymerase From Chenopodium Album L., K. Meißner, Sabine Heinhorst, Gordon C. Cannon, T. Börner

Faculty Publications

A DNA polymerase activity from mitochondria of the dicotyledonous angiosperm Chenopodium album L. was purified almost 9000 fold by successive column chromatography steps on DEAE cellulose, heparin agarose and ssDNA cellulose. The enzyme was characterized as a gamma-class polymerase, based on its resistance to inhibitors of the nuclear DNA polymerase alpha and its preference for poly(rA).(dT)12-18 over activated DNA in vitro. The molecular weight was estimated to be 80,000 - 90,000. A 3' to 5' exonuclease activity was found to be tightly associated with the DNA polymerase activity through all purification steps. This is the first report of an association …

Investigation Of The Β-Γ Phase Transition In Single Crystal Malononitrile By Polarized Raman Spectroscopy, S.J. Bonafede, Craig J. Eckhardt

Craig J. Eckhardt Publications

Temperature dependent, polarized Raman spectra in the lattice mode region for sublimed, single crystal malononitrile through the β-γ phase transition (T_c=294.7 K) are reported. Symmetry assignments and frequencies of vibrational modes are made and compared to previous studies. Nine out of 12 possible lattice modes are observed in each phase with three of the observed modes being affected by the phase transition. The temperature dependence of these three affected modes is attributed to cyano group and molecular dipole interactions between molecules in the crystal. The behavior of malononitrile through the β-γ phase transition is analogous to the …

Polymer Science And Technology For The 21sth Century, Gerald S. Kirshenbaum, Eli M. Pearce

Emeritus Faculty Author Gallery

No abstract provided.