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Articles 1 - 29 of 29
Full-Text Articles in Physical Sciences and Mathematics
Synthesizing Octahedral Polyomavirus Capsids For Cryogenic Electron Microscopy, Miles Robertson
Synthesizing Octahedral Polyomavirus Capsids For Cryogenic Electron Microscopy, Miles Robertson
Fall Student Research Symposium 2020
Polyomavirus capsids are polymorphic under different chemical conditions. These capsids have been synthesized artificially using purified VP1, the primary building block of the capsid. Five VP1 proteins come together and form a highly stable structure called a pentamer, and these pentamers can form capsids (Figure 1). Depending on chemical conditions, the capsids can form three distinct sizes: T=7, octahedral and icosahedral (Figure 2). Only one form is found in infectious virions, and its structure has been well studied. However, no high-resolution structure of the octahedral capsid currently exists. The goal of this research is to solve the structure of the …
Enabling Mars Farms Through Microbial Remediation Of Wastewater, Tyler Wallentine
Enabling Mars Farms Through Microbial Remediation Of Wastewater, Tyler Wallentine
Fall Student Research Symposium 2020
This research evaluates the capacity of photoheterotrophic purple non-sulfur bacteria to utilize wastewater organics to grow and produce nitrogen-rich biomass. Inhibitory components of wastewater are determined. A scaled up production system is designed and utilized to culture bacteria in wastewater. The application of this technology in the production of agriculturally viable amounts of nitrogen-rich biomass is evaluated in the context of a Mars mission and enabling agriculture in a barren environment.
Why Dogs Are Feared, Hannah Ericson
Why Dogs Are Feared, Hannah Ericson
Fall Student Research Symposium 2020
From German Shepherds to Pit bulls, a specific breed of dog is often singled out as being more dangerous than the others. There are stories and myths behind the behavior of such breeds, as well as simply looking scary. In this presentation, I will discuss why certain traits in dogs promote fear (such as dark coloring) and why certain breeds promote fear - such as a modern day prejudice that is quite similar to racism in the human society.
Cloning Type Iv-B Crispr System Into A Plasmid, Olivia Gornichec, Kailey Welch
Cloning Type Iv-B Crispr System Into A Plasmid, Olivia Gornichec, Kailey Welch
Fall Student Research Symposium 2020
Bacterial CRISPR-Cas systems have recently been repurposed as RNA-guided genome editors in research labs across the world. Yet CRISPR-Cas adaptive immune systems are very diverse and many systems remain uncharacterized. Discovering the structure and function of newly discovered and uncharacterized systems may further advance existing genome editing technologies, or lead to new ones. To better understand the function of the little-researched Type IV-B system we cloned the genes of a Type IV-B system from Mycobacterium J623 into a plasmid containing a target sequence of a Type IV-A and Type V system. The Type IV-B system was placed on the target …
The Impact Of Biological Components On A Dog's Personality, Kinsley Batson
The Impact Of Biological Components On A Dog's Personality, Kinsley Batson
Fall Student Research Symposium 2020
We interact with dogs every day, and they are often referred to as "man's best friend." But what makes a dog the happy-go-lucky, cuddly fur ball of happiness that so many love? Similar to humans, there is a nature vs. nurture debate on what shapes a dog's personality. While it is likely a mixture of both, I've researched a variety of biological components that help to make a dog a dog. Some of these include face shape, how their brain responds to audio stimuli, and a specific gene, also found in children with Williams syndrome, that is thought to make …
Pure Breeding At Its Finest, Justin Hunter
Pure Breeding At Its Finest, Justin Hunter
Fall Student Research Symposium 2020
This is a poster of my research on the affects pure breeding has on dogs and their health. There is a focus as well on the focus on neoteny and its affects on dogs.
Dogs In The Home Improve The Quality Of Life Of The People Living Inside, Tanner Stevenson
Dogs In The Home Improve The Quality Of Life Of The People Living Inside, Tanner Stevenson
Fall Student Research Symposium 2020
This poster explores how dogs improve the quality of life of the people they interact with. Regardless of underlying issues that the human faces, every dog helps to improve the situation of that human. From service animals helping to improve the quality of life of their owners in other ways than what meets the eye, to dogs improving the chance of allergy immunity for children, dogs impact the lives of humans for good. This project explores the way that studies have proven the worth of the dog in the home.
Chapter 1.2: Visualization Of Buffer Capacity With 3-D Topos: Buffer Ridges, Equivalence Point Canyons And Dilution Ramps, Garon C. Smith, Md Mainul Hossain
Chapter 1.2: Visualization Of Buffer Capacity With 3-D Topos: Buffer Ridges, Equivalence Point Canyons And Dilution Ramps, Garon C. Smith, Md Mainul Hossain
Water Topos: A 3-D Trend Surface Approach to Viewing and Teaching Aqueous Equilibrium Chemistry
The BufCap TOPOS software generates 3-D topographic surfaces for acid-base equilibrium studies that portray pH and buffer capacity behavior during titration and dilution procedures. Topo surfaces are created by plotting computed pH and buffer capacity values above a composition grid with volume of NaOH as the x-axis and overall system dilution as the y-axis. What emerge are surface features that correspond to pH and buffer behaviors in aqueous solutions. Topo surfaces are created for pH, log buffer capacity and linear buffer capacity. Equivalence point breaks become pH cliffs and logarithmic buffer capacity canyons that grow shallower with dilution. …
Chapter 1.1: 3-D Surface Visualization Of Ph Titration “Topos”: Equivalence Point Cliffs, Dilution Ramps And Buffer Plateaus, Garon C. Smith, Md Mainul Hossain, Patrick Maccarthy
Chapter 1.1: 3-D Surface Visualization Of Ph Titration “Topos”: Equivalence Point Cliffs, Dilution Ramps And Buffer Plateaus, Garon C. Smith, Md Mainul Hossain, Patrick Maccarthy
Water Topos: A 3-D Trend Surface Approach to Viewing and Teaching Aqueous Equilibrium Chemistry
3-D topos can be generated to visualize how pH behaves during titration and dilution procedures. The surfaces are constructed by plotting computed pH values above a composition grid with volume of base added in one direction and overall system dilution on the other. Surficial features correspond to behavior in aqueous solutions. Equivalence point breaks become cliffs that pinch out with dilution. Buffer effects become plateaus. Dilution alone generates 45o ramps. Sample surfaces are analyzed for acetic acid, CH3COOH (a weak monoprotic acid); hydrochloric acid, HCl (a strong acid); oxalic acid, HOOCCOOH (a weak diprotic acid) and L-histidine …
Mutating Lpar4 In The Visual System Using Crispr, Thomas A. Gonzalez
Mutating Lpar4 In The Visual System Using Crispr, Thomas A. Gonzalez
S.U.R.E Posters
The visual system is developed throughout the embryonic stage and is dictated by axon guidance molecules that tell the growing fibers of nerve cells, axons, where to grow. The ends of axons, called growth cones, continuously sprout out or collapse based on the axon guidance molecules. Research has shown that lysophosphatidic acid (LPA) causes growth cone collapse, so it is hypothesized that it is an axon guidance molecule. LPA binds to specific receptors, known as Lpars of which there are at least five known. Previous research indicates that Lpar 1,2, and 3 are not required in mice for growth cone …
Discovery Research For New Optical Materials, Kameron Johnson
Discovery Research For New Optical Materials, Kameron Johnson
S.U.R.E Posters
This project utilizes the MGI approach in order to discover new compounds at an accelerated rate. Novel materials for optical applications, such as luminescent scintillators, are desired for improvement of properties. Using density functional theory (DFT) calculations, new single-crystal scintillating materials can be optimized leading to more efficient scintillation. (5) Two existing compounds in the quaternary system Na-O-Si-Y were chosen and further modified using substitutions into proposed structures that can be investigated. The two original compounds, NaO4SiY and NaO26Si6Y9, were chosen and modified because of their already high density by substituting yttrium for lanthanum, sodium for potassium and yttrium for …
Elucidating The Effect Of The Antibiotic Tetracycline On The Regulatory Function Of The Guanidine Sensing Riboswitch Ykkcd, Thomas K. Sullivan
Elucidating The Effect Of The Antibiotic Tetracycline On The Regulatory Function Of The Guanidine Sensing Riboswitch Ykkcd, Thomas K. Sullivan
S.U.R.E Posters
The primary objective of this research is to develop an assay – one more feasible for undergraduate institutions than currently available methods – that will enable evaluation of the concomitant binding of, guanidine and tetracycline to the ykkCD bacterial guanidine sensor riboswitch. This noncoding regulatory RNA, in addition to guanidine, also recognizes tetracycline, a translation-inhibiting antibiotic, via a high-affinity aptamer domain. The resulting conformational change by the riboswitch upregulates the expression of genes that are downstream of this regulator, most of which are membrane transporter that expel toxins from bacteria. This phenomenon exemplifies the increasing issue of bacterial antibiotic resistance, …
Photoredox Mediated Alkylation Of Imines With Potassium Organotrifluoroborates In The Presence Of An Organic Photocatalyst, Jackson W. Barrett, Evan H. Thibodeaux, Molly A. Quetel, Eric J. Walters
Photoredox Mediated Alkylation Of Imines With Potassium Organotrifluoroborates In The Presence Of An Organic Photocatalyst, Jackson W. Barrett, Evan H. Thibodeaux, Molly A. Quetel, Eric J. Walters
S.U.R.E Posters
Our group is investigating the application of an organic photocatalyst, 9-mesityl-10-methyl acridinium tetrafluoroborate (Mes-Acr-Me), to the alkylation of aryl imines with potassium organotrifluoroborates. In the past, our group has employed an potassium isopropyltrifluoroborate for model reactions, but we desired to expand our BF3K scope to see the effects of variation in the alkyl group of the organotetrafluoroborate. In addition, we also wanted to study the substituent electronic effects in the imine, which was done using a series of competition experiments.
Using Nucleic Acid-Gold Nanoparticle Conjugate In The Fight Against Bacteria That Are Resistant To Tetracycline Antibiotics, Allen T. Livingston
Using Nucleic Acid-Gold Nanoparticle Conjugate In The Fight Against Bacteria That Are Resistant To Tetracycline Antibiotics, Allen T. Livingston
S.U.R.E Posters
Antibiotic resistance is major problem in modern medicine. Seventy percent of bacterial strains are resistant to at least one antibiotic, making treatment of bacterial infections ever more expensive and difficult. Currently, we are investigating the therapeutic potency of nucleic acid-gold nanoparticle conjugates as treatments against bacteria that are resistant to the antibiotic tetracycline. We hypothesize that by attaching RNA that binds to tetracycline to silver or gold nanoparticles the resulting conjugates will work as a “Trojan-horse” tetracycline-delivery vehicle that smuggles the antibiotic into the cell without being detected by cellular defense systems. Moreover, we reason that silver or gold ions …
Prologue: An Overview To Water Topos: A 3-D Trend Surface Approach To Viewing And Teaching Aqueous Equilibrium Chemistry, Garon C. Smith, Md Mainul Hossain
Prologue: An Overview To Water Topos: A 3-D Trend Surface Approach To Viewing And Teaching Aqueous Equilibrium Chemistry, Garon C. Smith, Md Mainul Hossain
Water Topos: A 3-D Trend Surface Approach to Viewing and Teaching Aqueous Equilibrium Chemistry
The “topo” approach to viewing and teaching aqueous equilibrium through 3-D trend surfaces is introduced. A list of the pedagogical resource categories that accompany each chapter is provided. We describe the “composition grids” that form the foundation for the trend surfaces. A roadmap for the subsequent chapters follows. Finally, a brief statement about the Excel-based computer software is provided.
Sulfur Dioxide From The Atmospheric Chemistry Experiment Satellite, Doug Cameron
Sulfur Dioxide From The Atmospheric Chemistry Experiment Satellite, Doug Cameron
College of Sciences Posters
The version 4.0 dataset from the Atmospheric Chemistry Experiment – Fourier Transform Spectrometer (ACE-FTS) on SCISAT, released in March of 2019, has sulfur dioxide (SO2) volume mixing ratio (VMR) profiles as a routine data product. From this dataset, global SO2 distributions between the altitudes of 10.5 km and 23.5 km are analyzed. The global distribution of all SO2 VMR data by altitude is broken down into 30° and 5° latitude zones. Seasonality of the global SO2 distribution is explored. Volcanic SO2 plumes are isolated in the dataset and compared with extinction data from the …
Universality Of Physical And Chemical Critical Effects In Liquid Mixture, Joshua Lang, Xingjian Wang, Pauline Norris
Universality Of Physical And Chemical Critical Effects In Liquid Mixture, Joshua Lang, Xingjian Wang, Pauline Norris
Research Horizons Day Posters
No abstract provided.
Understanding The Oxidative Chemistry Of Particulate Methane Monooxygenase Models., Thomas Jones
Understanding The Oxidative Chemistry Of Particulate Methane Monooxygenase Models., Thomas Jones
Research Horizons Day Posters
No abstract provided.
Automated Process Of Quantifying Scientific Images Using Fiji, Olivia Casimir
Automated Process Of Quantifying Scientific Images Using Fiji, Olivia Casimir
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Using Batman Software To Analyze Metabolic Changes In Type 1 Diabetes-Susceptible Rats, Connor Hall
Using Batman Software To Analyze Metabolic Changes In Type 1 Diabetes-Susceptible Rats, Connor Hall
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Kidney Tissue Preparation For 1h-Nmr Analysis And Colorimetric Activity Assay Of Mitochondria, Savannah Knight, James Wolfsberger
Kidney Tissue Preparation For 1h-Nmr Analysis And Colorimetric Activity Assay Of Mitochondria, Savannah Knight, James Wolfsberger
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Lew,1wr1 Rat Shows An Increased Risk Of Developing Malignant Forms Of Nafld, Luis Mercado
Lew,1wr1 Rat Shows An Increased Risk Of Developing Malignant Forms Of Nafld, Luis Mercado
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Reactions At The Critical Point Of Solution, Jason Mote
Reactions At The Critical Point Of Solution, Jason Mote
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Metabolomic Study Of The Lew.1wr1 Rat: Serum Artificial Mixture Validation, Jennifer S. Nix
Metabolomic Study Of The Lew.1wr1 Rat: Serum Artificial Mixture Validation, Jennifer S. Nix
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Magnetic Hyperthermia For Cancer Treatment, Çiğdem Elif Demirci Dönmez, Adem Dönmez
Magnetic Hyperthermia For Cancer Treatment, Çiğdem Elif Demirci Dönmez, Adem Dönmez
Science and Mathematical Science
The obtained results in this study clearly indicates the enhancing effect of polymer coating on hyperthermia efficiency. In a very recent study, the efficiency of the niclosamide-loaded hyperbranched polymerfunctionalized magnetic nanoparticles on mediated hyperthermia and niclosamide (an anticancer drug) bimodel therapy were investigated. The results in this study indicated that polymerfunctionalized nanoparticles showed sufficient temperature gain for magnetic hyperthermia.
Temporal Behavior Of The Individual Soft Microparticles: Understanding The Detection By Particle Impact Electrochemistry, Junaid Ahmed, Julio C. Alvarez
Temporal Behavior Of The Individual Soft Microparticles: Understanding The Detection By Particle Impact Electrochemistry, Junaid Ahmed, Julio C. Alvarez
Graduate Research Posters
Emerging progress of the Particle Impact Electrochemistry (PIE) technique has opened a novel field of detection and characterization of many analyte particles. 1 PIE comprises detection of changes in current when collisions of individual micro or nanoparticles are linked with an electrochemical event at the surface of an ultramicroelectrode (UME). 2 Being a rapid, low cost, and analyzing of one analyte at a time, PIE is widely used to characterize the shape, size distribution, and catalytic activity of nanoparticles. 2-5 To explore the scope of PIE for the detection of soft microparticles (absence of crystalline structure), ferrocene (Fc) trapped toluene-in-water …
Chemical Process Development, University Of North Dakota. Energy And Environmental Research Center
Chemical Process Development, University Of North Dakota. Energy And Environmental Research Center
EERC Brochures and Fact Sheets
Fact sheet on the Energy & Environmental Research Center’s (EERC’s) chemical process development capabilities.
Green Chemistry: The Oxidation Of Benzaldehyde Using Atmospheric Oxygen And N-Heterocyclic Carbenes As Catalysts, Alex Brody, John Morgan
Green Chemistry: The Oxidation Of Benzaldehyde Using Atmospheric Oxygen And N-Heterocyclic Carbenes As Catalysts, Alex Brody, John Morgan
Student Research Poster Presentations 2020
Oxidation is a vital process in organic and biochemical reactions. In particular, the oxidation of aromatic aldehydes to carboxylic acids and esters is a vital process used in many different environments. Benzaldehyde is one common subject of this type of reaction, used in the synthesis of benzoic acid and benzoate derivatives. Unfortunately, the industrial synthesis of these compounds uses harmful heavy metal oxidants such as Chromium(VI) and Manganese(VII), which are very harmful to the environment. We proposed to eliminate these pollutants by using atmospheric oxygen and an organic catalyst in a solvent free reaction. This reaction would then be microwaved …
Chemistry In Medicine, Olivia Visaggio, Alyssa Bondi, Matthew Gillingham, Hailey Loughlin
Chemistry In Medicine, Olivia Visaggio, Alyssa Bondi, Matthew Gillingham, Hailey Loughlin
Student Research Poster Presentations 2020
The chemistry behind medicine is important and necessary to study many different drugs and their effects. In this project, we focused on the chemical composition and mechanisms of various drugs. The drugs we focused on include Opioids, NSAIDs, and other medications, such as Benzodiazepines and antibiotics. For each drug, we provided its structure as well as the functional groups, which include a part of a molecule that is recognized based on its arrangement of atoms. Organic Chemistry provides individuals with an understanding of various organic compounds, and this field of study is important as it explains the ways in which …