Physical Sciences and Mathematics Commons^™

Halogenated Helicenes, Richard Wilbert Heiden

Honors Theses

Attempts at synthesizing certain halohelicenes for studies in the following areas are described: 1) the testing of a new method of resolving 2) electron spin resonance (ESR). Since the purpose of the study was twofold, the decision to synthesize monochloro derivatives of hexahelicene was based on the time element and the comparative ease in which these particular compounds were thought to have been brought about (i.e. in direct comparison to polyhalo and higher order helicenes). In addition to the traditional historical, theoretical, and experimental sections, an appendix contained a few suggestions relative to helicene research is included.

Calculations Of Total Energies For Neon Atom, Argon Atom And Neon Ion, Joseph Patrick Minehan

Honors Theses

This work shows that is is very difficult to guess the proper configuration of the spheres for most atoms. This is clearly shown in the argon calculations, where Bent suggested a configuration that would have lowest energy, but it turned out to have the highest energy of those calculated. This shows the need to have a method to give the configuration of the lowest energy that depends very little on human insight.

Synthetic Approaches To Tris (1-B, 8-B'-Naphthyl) Diboron, William Karl Goerich

Honors Theses

The purpose of this project was the synthesis of tris(l-B, 8-B'­naphthyl)diboron. The synthesis route attempted was the preparation of 1,8-dibromonaphthalene from 1,8-diaminonaphthalene by tetrazotization followed by a Sandmeyer reaction, treatment of the dibromo compound with n-butyllithium to give 1,8-dilithionaphthalene and subsequent addition of boron trifluoride to give the product.

Synthesis Of N-Methyl-N-Phenylaminomethyltrimethylsilane And N, N-Dimethylanilinomethyltrimethylsilyl Iodide, Mark Stuart Lichtenstein

Honors Theses

N-Methyl-N-Phenylaminomethyltrimethylsilane (I) has been prepared by heating an ethereal solution of lithium N-Methyl-anilide and chloromethyltrimethylsilane in a sealed flask for two days at 110°. The peak ratios in the NMR spectrum of the product did not correspond to these expected for I but suggested a different product, N-Methyl-N-Trimethylsilylaniline (II). Elemental analysis favored II although it could also be interpreted to support I. The spectra of derivatives, and the substance’s stability to hydrochloric acid were characteristic of I. Tentative identification of ethylene as a by-product, and a small degree of reaction with hydrochloric acid support the presence of II, but only …

Stability Of 1-Substituted Adenines, Walter Frederick Floser

Honors Theses

1-β-Hydroxyethyladenine was prepared by the reaction of ethylene chlorohydrin with adenine at 76° C. It was separated from the reaction mixture by use of a Dowex 50W-X8 cation exchange chromatography column and a linear gradient elution system. I was placed in aqueous alkaline solution for two weeks and checked at different intervals to determine its stability. I was also refluxed in an aqueous alkaline solution for 70 min. and its stability was checked. I proved to be stable under all conditions.

Photochemical Reduction Of Benzophenone By 2-Butyne-L, 4-Diol And Photochemical Solvolysis Reactions Of Beta-Phenethyl Compounds, Kenneth Lawrence Gordon

Honors Theses

The irradiation of a dioxane solution of benzophenone in the presence of 2-butyne-1, 4-diol leads to reduction of the ketone rather than addition across the triple bond of the alkyne. However, great difficulty was encountered in identifying the product due to the formation of an organic complex involving benzopinacol and the dioxane. Nuclear magnetic resonance and ultraviolet spectral data confirm the presence of the complex. An attempt was made to induce a known ground state reaction by photochemical means. This ground state reaction is known to proceed through an ethylene phenonium ion intermediate. Both β-phenethyl bromide and β-phenethyltrimethylammonium tetrafluoroborate were …

Determination Of Ring Orientation In Diphenylmethane And Derivatives, Patrick Michael Comi

Honors Theses

Nuclear Magnetic Resonance Spectrometry, like infrared, visible, and ultraviolet spectrometry is a form of absorption spectrometry. Certain nuclei can absorb electromagnetic radiation in the radiofrequency range. These nuclei are able to absorb this energy because they “spin” about their center axis generating a dipole along it. Protons are among those nuclei that absorb radiofrequency energies. If a proton is placed in a magnetic field its dipole can be in one of two possible orientations. It can be in a low energy state aligned with the field, or a high energy state, a spinning proton will process about an axis at …

Effect Of Trace Metals On Growth Rate Of Algae, Gabriel H. Srouji

Honors Theses

Heavy metals, although only in traces, are essential for all forms of life. They are taken up by the living cell in the form of cations, and their uptake is strictly regulated because most or all of them are toxic in excess. A remarkable specificity has been found: seldom can an excess of one essential metal prevent the damage caused by deficiency of another. In fact, such an excess often increase the injurious effect of deficiency.

Metal-binding substances, many of which function by chelation, form a class of substances which have furnished many useful drugs and other substances of value …