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2-Allylphenyl Glycosides As Complementary Building Blocks For Oligosaccharide And Glycoconjugate Synthesis, Hemali D. Premathilake, Alexei V. Demchenko
2-Allylphenyl Glycosides As Complementary Building Blocks For Oligosaccharide And Glycoconjugate Synthesis, Hemali D. Premathilake, Alexei V. Demchenko
Alexei Demchenko
The O-allylphenyl (AP) anomeric moiety was investigated as a new leaving group that can be activated for chemical glycosylation under a variety of conditions, through both direct and remote pathways. Differentiation between the two activation pathways was achieved in a mechanistic study. The orthogonal-type activation of the AP moiety along with common thioglycosides allows for the execution of efficient oligosaccharide assembly.