Physical Sciences and Mathematics Commons^™

Investigation Of Complex Formation By Oligomers Of Cytosine And Guanosine, Steven Roberts Davis

Chemistry & Biochemistry Theses & Dissertations

Duplex formation between oligo(C:G) _n where n=3 to 4 was shown not to occur under conditions favorable for duplex formation between poly G and poly C. Instead, a stable guano sine self-structure was found to form which a T_m of 50°C for (Gp)₃ and 80°C for (Gp)₄ at strand concentrations of 10^-5M in 1M NaCl. Neither a duplex nor a self-structure formed in the absence of salt.

Oligomers of guanosine and cytosine were obtained by basic hydrolysis and separated according to chain length using DEAE Sephadex column chromatography. Separation of cytosine oligomers with chain lengths …

Fluoride As A Therapeutic Drug In Osteoporosis Treatment, Rita Priyadarshani Francis

Honors Theses

The use of fluoride as a therapeutic drug is not a novel idea. Studies dealing with the effects of fluoride on the skeletal system date back to the late 1960's. This paper will define osteoporosis, examine methods of detection, and will discuss various methods of treatment with emphasis on the use of fluoride supplements in the form of tablets or fluorinated drinking water.