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Full-Text Articles in Physical Sciences and Mathematics

Driving Under The Influence Of Drugs: Status In New York City And Development Of New Analytical Tools, Kayla Marschke May 2022

Driving Under The Influence Of Drugs: Status In New York City And Development Of New Analytical Tools, Kayla Marschke

Student Theses

Driving under the influence of drugs (DUID) cases have increased in recent years. According to NHTSA, drug use among fatally injured drivers who were tested for drugs rose from 25% in 2007 to 61.4% in 2020. Knowing what drugs are used by the drivers and developing new analytical tools to detect them are essential to prevent this type of cases. The goals of this study were two-fold: 1) To investigate the prevalence of drugs and drug combinations in New York City based on data provided by the Office Chief Medical Examiner (2018-2019); 2) To develop and validate an analytical method …


Determination Of Anxiolytic And Antidepressant Medicines In New York City Wastewater Samples, Jasmine J. Gayle May 2019

Determination Of Anxiolytic And Antidepressant Medicines In New York City Wastewater Samples, Jasmine J. Gayle

Student Theses

Wastewater-based epidemiology (WBE) provides information about a population’s exposure to certain chemical agents, such as drugs of abuse and medicines, by the analysis of human biomarkers, also known as excretion products, in wastewater samples. Although this is a growing field worldwide, mainly in Europe, Oceania, and Asia, limited data from the US are currently available. We developed and validated an analytical method to quantitatively and qualitatively determine the presence of commonly prescribed drugs to treat anxiety (alprazolam, buspirone, clonazepam, lorazepam, and propranolol) and depression (bupropion, citalopram, clomipramine, duloxetine, fluoxetine, imipramine, paroxetine, sertraline, and venlafaxine) in wastewater using liquid chromatography tandem …


Detection Of Cathinone And Mephedrone In Plasma By Lc-Ms/Ms Using Standard Addition Quantification Technique, Theron W. Ng-A-Qui May 2017

Detection Of Cathinone And Mephedrone In Plasma By Lc-Ms/Ms Using Standard Addition Quantification Technique, Theron W. Ng-A-Qui

Student Theses

Designer drugs are structural analogs of Drug Enforcement Agency (DEA) Schedule I and II substances. They are synthesized to mimic the effects of illegal drugs of abuse and to bypass the provisions of drug regulations. Despite the increased availability of designer drugs, few studies have focused on specific analytical extraction techniques for their detection and quantification in biological samples. Solid phase extraction (SPE) is the most commonly used technique for sample preparation. The purpose of this study is to evaluate the extraction efficiency of the various SPE columns with different sorbent materials for two designer drugs, cathinone and mephedrone in …