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Full-Text Articles in Physical Sciences and Mathematics
Methodology Development For The Implementation Ofmicrofluidic Mixers, Tahir Butt, Gautam Mahajan
Methodology Development For The Implementation Ofmicrofluidic Mixers, Tahir Butt, Gautam Mahajan
Undergraduate Research Posters 2018
Microfluidic platforms have been widely regarded as defining technologies for the development of chemical and biological synthesis and analysis systems, due to benefits associated with reduced reactant consumption, increases by orders of magnitude of the surface-to-volume ratios, and greatly enhanced control over reactions variables such as temperature and pressure. However, one of the bottlenecks for their wide application is the difficulty in achieving mixing, given the typical laminar flows in these systems. In this work we implement experimentally, various strategies using geometrical features to control the fluid motion and induce stirring flows. The mixers are fabricated using soft-lithography in PDMS …
Implementation Of A Reverse Staggered-Herringbone Microfluidic Mixer For High-Throughput Polymeric Nanoparticles Synthesis, Alexa Roberts
Implementation Of A Reverse Staggered-Herringbone Microfluidic Mixer For High-Throughput Polymeric Nanoparticles Synthesis, Alexa Roberts
Undergraduate Research Posters 2018
The goal of this research is to implement and optimize the operating conditions of a microfluidic mixer to synthesize polymeric nanoparticles (NPs) in a high-throughput fashion. Using a reverse staggered-herringbone microfluidic mixer that we recently designed, the effects of experimental conditions such as flowrate and reactant composition on NP characteristics were investigated and optimized. The device design allowed for physical contact between two streams of fluids – one containing poly(lactic-co-glycolic acid; PLGA) in acetonitrile and the other deionized water, to allow for efficient mixing and NP precipitation to occur. The resulting NPs were characterized using dynamic light scattering (DLS) and …
Boundary Effects On The Locomotion Of Active Janus Particles, Marola W. Issa, Nicky R. Baumgartner
Boundary Effects On The Locomotion Of Active Janus Particles, Marola W. Issa, Nicky R. Baumgartner
Undergraduate Research Posters 2018
Self-propelled or “active” micrometer scale particles are capable of supplying local mechanical work, necessary for microscale cargo delivery and useful in other applications within bioimaging and sensing. Research in the last decade has focused on developing, measuring, and manipulating the locomotion mechanisms of active particles in simple environments. However, many applications will be in complex environments with nearby boundaries or variations in physiochemical cues. This poster reports the directed motion of platinum coated polystyrene particles at infinite dilution in the presence of H2O2, which acts as a fuel to drive motion. A transport mechanism called “diffusiophoresis” drives motion of the …
P1: Salt Concentration And Ph Affect The Size Of Elastin-Like Polypeptide Nanoparticles, Bryce Noe, Ilona Tsuper, Daniel Terano, Richard Schmitt
P1: Salt Concentration And Ph Affect The Size Of Elastin-Like Polypeptide Nanoparticles, Bryce Noe, Ilona Tsuper, Daniel Terano, Richard Schmitt
Undergraduate Research Posters 2017
The transport of therapeutic drugs to specific tissues in the body can be accomplished using nanoparticles that encapsulate the drugs. Elastin-like polypeptides (ELP) is a class of materials that can reversibly form such nanoparticles in response to environmental cues. FLPs transition from soluble compounds to a phase separated system under particular solution conditions and have been used to produce temperature responsive surfactants. When these ELP surfactants are above their transition temperature, they spontaneously form energetically stable spherical micelles. When the temperature drops below the transition temperature, the micelles break apart and the ELP goes into solution. The size of these …
Evaluation Of Cetane Values Of Glycerolipids Extracted From Algae Scenedesmus Dimorphus Grown In Various Salinity Concentrations Using Gas Chromatography And Mass Spectrometry (Gc-Ms), Paul Lin, Chandana Mannem
Evaluation Of Cetane Values Of Glycerolipids Extracted From Algae Scenedesmus Dimorphus Grown In Various Salinity Concentrations Using Gas Chromatography And Mass Spectrometry (Gc-Ms), Paul Lin, Chandana Mannem
Undergraduate Research Posters 2017
Algae's ability to store lipids, renewability, and potentially safer for the environment has made it a promising alternative fuel source. An industry rating for a biofuel's potential is the cetane value, which is a measure of a fuel's quality related to various glycerolipid concentrations. Growing conditions will affect lipid profile in algae, thereby affecting the cetane value. This project will attempt to identify changes in the centane value of the algae Scenedesmus dimorphus grown in various salinity concentrations. Scenedesmus dimorphus is the algae chosen for this experiment because of its ability to rapidly grow under harsh conditions. In this experiment …
P2: Light Scattering Study Of The Size And Shape Of Mixed Elastin-Like Polypeptide Micelles, Ilona Tsuper, Daniel Terrano, Bryce Noe
P2: Light Scattering Study Of The Size And Shape Of Mixed Elastin-Like Polypeptide Micelles, Ilona Tsuper, Daniel Terrano, Bryce Noe
Undergraduate Research Posters 2017
Elastin-Like Polypeptides (ELP) can be used to form thermoreversible vehicles for drug delivery systems. The ELP nanoparticles are composed of three-armed star polypeptides. Each of the three arms extending from the negatively charged foldon domain include 20 repeats of the (GVGVP) amino acid sequence. In addition, linear constructs composed of 40 repeats of the same (GVGVP) sequence are introduced into the system. The mixed ELP polymer system is soluble at room temperature and becomes insoluble at the transition temperature (~ 50°C) forming micelles with the foldons on the exterior and linear constructs at the core. Above the transition, the size …
Going Green: Experimental Adaptation Of Scenedesmus Dimorphus To Marine Conditions, Mohammed Khalil
Going Green: Experimental Adaptation Of Scenedesmus Dimorphus To Marine Conditions, Mohammed Khalil
Undergraduate Research Posters 2017
Algae has gained some interest as the need for alternative fuels becomes more pressing. Reliance on fossil fuels is causing our environment and economy harm, and is not sustainable moving forward. Lipid rich algae strains can be used in the production of biofuels, and provide an alternative fuel source. One challenge facing the prospect of algae as a fuel source is that lipid rich algae grows exclusively in freshwater. Considering the scarcity and cost to use freshwater for algae growth, interest has grown in the possibility of adapting lipid rich, freshwater algae to a seawater environment. Seawater can have up …
Fabricating Non-Close Packed Colloidal Monolayers For Ion Irradiation Templates, Nandini Padaraju
Fabricating Non-Close Packed Colloidal Monolayers For Ion Irradiation Templates, Nandini Padaraju
Undergraduate Research Posters 2017
Due to their unique properties, anisotropic nanoparticles are desirable components for future applications yet there are few processes capable of fabricating nanoparticle impregnated coatings for the manufacturing environment. Our work seeks to develop new masking techniques for the production of the templated substrates that will induce ordered nanoparticle films. Specifically, we are fabricating non-close packed colloidal monolayers onto silicon substrates, which then serve as the template for ion irradiation. The first steps to creating this monolayer are obtaining a spin-coated poly(vinyl alcohol) (PVA) thin film of ~200 nm and a close-packed colloidal monolayer using a peltier heater. We achieved a …