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On The Estimation Of Intracluster Correlation For Time-To-Event Outcomes In Cluster Randomized Trials, Sumeet Kalia
On The Estimation Of Intracluster Correlation For Time-To-Event Outcomes In Cluster Randomized Trials, Sumeet Kalia
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Cluster randomized trials (CRTs) involve the random assignment of intact social units rather than independent subjects to intervention groups. Time-to-event outcomes often are endpoints in CRTs where the intracluster correlation coefficient (ICC) serves as a descriptive parameter to assess the similarity among outcomes in a cluster. However, estimating the ICC in CRTs with time-to-event outcomes is a challenge due to the presence of censored observations. The ICC is estimated for two CRTs using the censoring indicators and observed outcomes.
A simulation study explores the effect of administrative censoring on estimating the ICC. Results show that the ICC estimators derived from …