Open Access. Powered by Scholars. Published by Universities.®

Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

Biostatistics

University of South Carolina

Theses/Dissertations

2019

Hazard discrimination summary

Articles 1 - 1 of 1

Full-Text Articles in Physical Sciences and Mathematics

Extension Of Risk-Based Measure Of Time-Varying Prognostic Discrimination For Survival Models, Shujie Chen Jul 2019

Extension Of Risk-Based Measure Of Time-Varying Prognostic Discrimination For Survival Models, Shujie Chen

Theses and Dissertations

The Cox proportional hazards (PH) model and time dependent PH model are the most popular survival models in survival analysis. The hazard discrimination summary HDS(t) proposed by Liang and Heagerty [2017] is used to evaluate the mean hazard difference between cases and controls at time t. Liang and Heagerty [2017] evaluated the discrimination performance under the PH model and time dependent PH model with right censoring.

In this thesis, first, we further investigate their method via comprehensive simulations including 1) We extend the simulation in Liang and Heagerty [2017] under the PH model by adding more scenarios such as different …