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Full-Text Articles in Physical Sciences and Mathematics

Random Regression Models Based On The Elliptically Contoured Distribution Assumptions With Applications To Longitudinal Data, Alfred A. Bartolucci, Shimin Zheng, Sejong Bae, Karan P. Singh May 2017

Random Regression Models Based On The Elliptically Contoured Distribution Assumptions With Applications To Longitudinal Data, Alfred A. Bartolucci, Shimin Zheng, Sejong Bae, Karan P. Singh

Shimin Zheng

We generalize Lyles et al.’s (2000) random regression models for longitudinal data, accounting for both undetectable values and informative drop-outs in the distribution assumptions. Our models are constructed on the generalized multivariate theory which is based on the Elliptically Contoured Distribution (ECD). The estimation of the fixed parameters in the random regression models are invariant under the normal or the ECD assumptions. For the Human Immunodeficiency Virus Epidemiology Research Study data, ECD models fit the data better than classical normal models according to the Akaike (1974) Information Criterion. We also note that both univariate distributions of the random intercept and …


Bayesian Analysis Of Discrete Skewed Laplace Distribution, A. Hossianzadeh, K Zare Nov 2016

Bayesian Analysis Of Discrete Skewed Laplace Distribution, A. Hossianzadeh, K Zare

Journal of Modern Applied Statistical Methods

The discrete skewed Laplace distribution is a flexible distribution with integer domain and simple closed form that can be applied to model count data. Parameters are estimated under empirical Bayes (EB) analysis and comparison are made between the Bayesian parameter estimation and classical parameter estimation, i.e. the maximum likelihood (ML) approach. The results show that the Bayesian parameter estimations are preferable.


Developing Prediction Equations For Fat Free Lean In The Presence Of An Unknown Amount Of Proportional Measurement Error, Zachary J. Hass, Bruce A. Craig, Allan Schinckel May 2016

Developing Prediction Equations For Fat Free Lean In The Presence Of An Unknown Amount Of Proportional Measurement Error, Zachary J. Hass, Bruce A. Craig, Allan Schinckel

Conference on Applied Statistics in Agriculture

Published prediction equations for fat-free lean mass are widely used by producers for carcass evaluation. These regression equations are commonly derived under the assumption that the predictors are measured without error. In practice, however, it is known that some predictors, such as backfat and loin muscle depth, are measured imperfectly with variance that is proportional to the mean. Failure to account for these measurement errors will cause bias in the estimated equation. In this paper, we describe an empirical Bayes approach, using technical replicates, to accurately estimate the regression relationship in the presence of proportional measurement error. We demonstrate, via …


Developing Prediction Equations For Carcass Lean Mass In The Prescence Of Proportional Measurement Error, Zachary J. Hass, Ziqi Zhou, Bruce A. Craig Apr 2014

Developing Prediction Equations For Carcass Lean Mass In The Prescence Of Proportional Measurement Error, Zachary J. Hass, Ziqi Zhou, Bruce A. Craig

Conference on Applied Statistics in Agriculture

Published prediction equations for carcass lean mass are widely used by commercial pork producers for carcass valuation. These regression equations have been derived under the assumption that the predictors, such as back fat depth, are measured without error. In practice, however, it is known that these measurements are imperfect, with a variance that is proportional to the mean. In this paper, we consider both a linear and quadratic true relationship and compare regression fits among two methods that account for this error versus simply ignoring the additional error. We show that biased estimates of the relationship result if measurement error …


A Non-Parametric Empirical Bayes Approach For Estimating Transcript Abundance In Un-Replicated Next-Generation Sequencing Data, Sanvesh Srivastava, R. W. Doerge Apr 2010

A Non-Parametric Empirical Bayes Approach For Estimating Transcript Abundance In Un-Replicated Next-Generation Sequencing Data, Sanvesh Srivastava, R. W. Doerge

Conference on Applied Statistics in Agriculture

Empirical Bayes approaches have been widely used to analyze data from high throughput sequencing devices. These approaches rely on borrowing information available for all the genes across samples to get better estimates of gene level expression. To date, transcript abundance in data from next generation sequencing (NGS) technologies has been estimated using parametric approaches for analyzing count data, namely – gamma-Poisson model, negative binomial model, and over-dispersed logistic model. One serious limitation of these approaches is they cannot be applied in absence of replication. The high cost of NGS technologies imposes a serious restriction on the number of biological replicates …


Random Regression Models Based On The Elliptically Contoured Distribution Assumptions With Applications To Longitudinal Data, Alfred A. Bartolucci, Shimin Zheng, Sejong Bae, Karan P. Singh Nov 2003

Random Regression Models Based On The Elliptically Contoured Distribution Assumptions With Applications To Longitudinal Data, Alfred A. Bartolucci, Shimin Zheng, Sejong Bae, Karan P. Singh

Journal of Modern Applied Statistical Methods

We generalize Lyles et al.’s (2000) random regression models for longitudinal data, accounting for both undetectable values and informative drop-outs in the distribution assumptions. Our models are constructed on the generalized multivariate theory which is based on the Elliptically Contoured Distribution (ECD). The estimation of the fixed parameters in the random regression models are invariant under the normal or the ECD assumptions. For the Human Immunodeficiency Virus Epidemiology Research Study data, ECD models fit the data better than classical normal models according to the Akaike (1974) Information Criterion. We also note that both univariate distributions of the random intercept and …