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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost Dec 2023

Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost

All Dissertations

In confocal single-molecule FRET experiments, the joint distribution of FRET efficiency and donor lifetime distribution can reveal underlying molecular conformational dynamics via deviation from their theoretical Forster relationship. This shift is referred to as a dynamic shift. In this study, we investigate the influence of the free energy landscape in protein conformational dynamics on the dynamic shift by simulation of the associated continuum reaction coordinate Langevin dynamics, yielding a deeper understanding of the dynamic and structural information in the joint FRET efficiency and donor lifetime distribution. We develop novel Langevin models for the dye linker dynamics, including rotational dynamics, based …


Models For Decision-Making - Second Edition, Steven Cosares, Fred Rispoli Jan 2023

Models For Decision-Making - Second Edition, Steven Cosares, Fred Rispoli

Open Educational Resources

Decision-Making often refers to a multi-stage process that starts with some form of introspection or reflection about a situation in which a person or group of people find themselves. These ruminations usually lead to series of questions that need to be answered, or to a set of data that needs to be collected and analyzed, or to some calculations that need to be performed before someone can be in a position to make informed decisions and take appropriate actions.

We provide some simple examples of Quantitative Models, which are often found in a decision-making situation. We focus on the use …


Spotting K-Tricaps In Spot It!, Jenarah Skyara Lara Jan 2023

Spotting K-Tricaps In Spot It!, Jenarah Skyara Lara

Senior Projects Spring 2023

The card game “SPOT IT!” consists of 55 cards, with 8 symbols appearing on each card. Every pair of cards has exactly one symbol in common, and the goal of the game is to be the first person to find this symbol. An alternate way to play the game is to find sets of 3 cards that have the same symbol in common. We will use combinatorics, probability, and finite projective geometry to analyze the structure of the game. The game “SPOT IT!” can be viewed as the projective plane of order 7. However, we can construct a similar game …