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Full-Text Articles in Physical Sciences and Mathematics

Analytical And Numerical Analysis Of The Sirs Model, Catherine Nguyen May 2024

Analytical And Numerical Analysis Of The Sirs Model, Catherine Nguyen

Student Research Submissions

Mathematical models in epidemiology describe how diseases affect and spread within a population. By understanding the trends of a disease, more effective public health policies can be made. In this paper, the Susceptible-Infected-Recovered-Susceptible (SIRS) Model was examined analytically and numerically to compare with the data for Coronavirus Disease 2019 (COVID-19). Since the SIRS model is a complex model, analytical techniques were used to solve simplified versions of the SIRS model in order to understand general trends that occur. Then by Euler's Method, the Runge-Kutta Method, and the Predictor-Corrector Method, computational approximations were obtained to solve and plot the SIRS model. …


Tools For Biomolecular Modeling And Simulation, Xin Yang Apr 2024

Tools For Biomolecular Modeling And Simulation, Xin Yang

Mathematics Theses and Dissertations

Electrostatic interactions play a pivotal role in understanding biomolecular systems, influencing their structural stability and functional dynamics. The Poisson-Boltzmann (PB) equation, a prevalent implicit solvent model that treats the solvent as a continuum while describes the mobile ions using the Boltzmann distribution, has become a standard tool for detailed investigations into biomolecular electrostatics. There are two primary methodologies: grid-based finite difference or finite element methods and body-fitted boundary element methods. This dissertation focuses on developing fast and accurate PB solvers, leveraging both methodologies, to meet diverse scientific needs and overcome various obstacles in the field.


Volatility Modeling Of Time Series Using Fractal And Self-Similarity Models, William Kubin May 2023

Volatility Modeling Of Time Series Using Fractal And Self-Similarity Models, William Kubin

Open Access Theses & Dissertations

The study uses various methods to compare financial and geophysical time series scaling parameters and long-term memory behavior. The Cantor Detrended Fluctuation Analysis (CDFA) method is proposed to provide more accurate estimates of Hurst exponents. The CDFA method is applied to real-time series and the results are verified. The study also analyzes the memory behavior of daily Covid-19 cases before and after the announcement of effective vaccines. Low and high-frequency dataâ??s influence on the Hurst Index estimation is investigated, and a new PCDFA method is proposed. The stability of the Dow Jones Industrial Average is analyzed using a multi-scale normalized …


Functional Data Analysis Of Covid-19, Nichole L. Fluke Nov 2022

Functional Data Analysis Of Covid-19, Nichole L. Fluke

Mathematics & Statistics ETDs

This thesis deals with Functional Data Analysis (FDA) on COVID data. The Data involves counts for new COVID cases, hospitalized COVID patients, and new COVID deaths. The data used is for all the states and regions in the United States. The data starts in March 1st, 2020 and goes through March 31st, 2021. The FDA smooths the data and looks to see if there are similarities or differences between the states and regions in the data. The data also shows which states and regions stand out from the others and which ones are similar. Also shown …


Machine Learning Model Comparison And Arma Simulation Of Exhaled Breath Signals Classifying Covid-19 Patients, Aaron Christopher Segura Aug 2022

Machine Learning Model Comparison And Arma Simulation Of Exhaled Breath Signals Classifying Covid-19 Patients, Aaron Christopher Segura

Mathematics & Statistics ETDs

This study compared the performance of machine learning models in classifying COVID-19 patients using exhaled breath signals and simulated datasets. Ground truth classification was determined by the gold standard Polymerase Chain Reaction (PCR) test results. A residual bootstrapped method generated the simulated datasets by fitting signal data to Autoregressive Moving Average (ARMA) models. Classification models included neural networks, k-nearest neighbors, naïve Bayes, random forest, and support vector machines. A Recursive Feature Elimination (RFE) study was performed to determine if reducing signal features would improve the classification models performance using Gini Importance scoring for the two classes. The top 25% of …


Relationships Between Covid-19 Infection Rates, Healthcare Access, Socioeconomic Status, And Cultural Diversity, Marghece P. J. Barnes Aug 2022

Relationships Between Covid-19 Infection Rates, Healthcare Access, Socioeconomic Status, And Cultural Diversity, Marghece P. J. Barnes

Boise State University Theses and Dissertations

The COVID-19 pandemic has had a disproportionate impact on racial and ethnic minority groups, with high infection rates throughout those communities. There are a complex set of factors that account for COVID-19 disparities. Focusing on infection and death rates alone without also examining health equity, underestimates the true impact of the pandemic. To gain a more clear understanding of COVID-19’s impact in these communities, we analyzed the relationship between state COVID-19 infection rates with social determinants of health: cultural diversity, health care access, and socioeconomic status. Our approach to identifying this relationship was to estimate infection rates by fitting John …


Could Cultures Determine The Course Of Epidemics And Explain Waves Of Covid-19?, Md Salman Rahman Aug 2022

Could Cultures Determine The Course Of Epidemics And Explain Waves Of Covid-19?, Md Salman Rahman

Theses and Dissertations

Coronavirus Disease (COVID-19), caused by the SARS-CoV-2 virus, is an infectious disease that quickly became a pandemic spreading with different patterns in each country. Travel bans, lockdowns, social distancing, and non-essential business closures caused significant economic disruptions and stalled growth worldwide in the pandemic’s first year. In almost every country, public health officials forced and/or encouraged Nonpharmaceutical Interventions (NPIs) such as contact tracing, social distancing, masks, and quarantine. Human behavioral decision-making regarding social isolation significantly impedes global success in containing the pandemic. This thesis focuses on human behaviors and cultures related to the decision-making of social isolation during the pandemic. …


A Network Analysis Of Covid-19 In The United States, Joseph C. Mcguire Jun 2022

A Network Analysis Of Covid-19 In The United States, Joseph C. Mcguire

Master's Theses

Through methods in network theory and time-series analysis, we will analyze the spread of COVID-19 in the United States by determining trends in state-by-state daily cases through a network construction. Previous researchers have found frameworks for approximating the spread of the COVID-19 pandemic and identifying potential rises in cases by a network construction based on correlation of cases between regions [1]. Applying this network construction we determine how this network and its structure act as a predictor for overall COVID-19 cases in the United States by preforming a trend analysis on a variety of network statistics and US COVID-19 cases.


Decision-Analytic Models Using Reinforcement Learning To Inform Dynamic Sequential Decisions In Public Policy, Seyedeh Nazanin Khatami Mar 2022

Decision-Analytic Models Using Reinforcement Learning To Inform Dynamic Sequential Decisions In Public Policy, Seyedeh Nazanin Khatami

Doctoral Dissertations

We developed decision-analytic models specifically suited for long-term sequential decision-making in the context of large-scale dynamic stochastic systems, focusing on public policy investment decisions. We found that while machine learning and artificial intelligence algorithms provide the most suitable frameworks for such analyses, multiple challenges arise in its successful adaptation. We address three specific challenges in two public sectors, public health and climate policy, through the following three essays. In Essay I, we developed a reinforcement learning (RL) model to identify optimal sequence of testing and retention-in-care interventions to inform the national strategic plan “Ending the HIV Epidemic in the US”. …


Classification And Keyword Identification Of Covid 19 Misinformation On Social Media: A Framework For Semantic Analysis, Grace Y. Smith Mar 2022

Classification And Keyword Identification Of Covid 19 Misinformation On Social Media: A Framework For Semantic Analysis, Grace Y. Smith

Theses and Dissertations

The growing surge of misinformation among COVID-19 communication can pose great hindrance to truth, magnify distrust in policy makers and/or degrade authorities’ credibility, and it can even harm public health. Classification of textual context on social media data relating to COVID-19 is an effective tool to combat misinformation on social media platforms. In this research, Twitter data was leveraged to 1) develop classification methods to detect misinformation and identify Tweet sentiment with respect to COVID-19 and 2) develop a human-in-the-loop interactive framework to enable identification of keywords associated with social context, here, being misinformation regarding COVID-19. 1) Six fusion-based classification …


Grouping Algorithms For Informative Array Testing In Disease Surveillance, David Sokolov Jan 2021

Grouping Algorithms For Informative Array Testing In Disease Surveillance, David Sokolov

Graduate Theses, Dissertations, and Problem Reports

In order to maintain normal operations and prevent unnecessary morbidity and mortality during times of disease outbreak, institutions find a need to conduct frequent and widespread testing of their constituents, often under significantly limited testing resource constraints. Faced with the challenge of how best to allo- cate these limited resources to maximum effect, institutions are increasingly turning to group (or “pooled”) testing, which involves testing strategically-chosen groups of patient samples rather than individual samples, producing significant testing resource savings under certain regimes of disease prevalence. While group test- ing can be conducted without any a priori knowledge of individual disease …


Modeling Coupled Disease-Behavior Dynamics Of Sars-Cov-2 Using Influence Networks, Juliana C. Taube Jan 2021

Modeling Coupled Disease-Behavior Dynamics Of Sars-Cov-2 Using Influence Networks, Juliana C. Taube

Honors Projects

SARS-CoV-2, the virus that causes COVID-19, has caused significant human morbidity and mortality since its emergence in late 2019. Not only have over three million people died, but humans have been forced to change their behavior in a variety of ways, including limiting their contacts, social distancing, and wearing masks. Early infectious disease models, like the classical SIR model by Kermack and McKendrick, do not account for differing contact structures and behavior. More recent work has demonstrated that contact structures and behavior can considerably impact disease dynamics. We construct a coupled disease-behavior dynamical model for SARS-CoV-2 by incorporating heterogeneous contact …


Multi-Level Small Area Estimation Based On Calibrated Hierarchical Likelihood Approach Through Bias Correction With Applications To Covid-19 Data, Nirosha Rathnayake Dec 2020

Multi-Level Small Area Estimation Based On Calibrated Hierarchical Likelihood Approach Through Bias Correction With Applications To Covid-19 Data, Nirosha Rathnayake

Theses & Dissertations

Small area estimation (SAE) has been widely used in a variety of applications to draw estimates in geographic domains represented as a metropolitan area, district, county, or state. The direct estimation methods provide accurate estimates when the sample size of study participants within each area unit is sufficiently large, but it might not always be realistic to have large sample sizes of study participants when considering small geographical regions. Meanwhile, high dimensional socio-ecological data exist at the community level, providing an opportunity for model-based estimation by incorporating rich auxiliary information at the individual and area levels. Thus, it is critical …