Physical Sciences and Mathematics Commons^™

Region Detection & Segmentation Of Nissl-Stained Rat Brain Tissue, Alexandro Arnal

Open Access Theses & Dissertations

People who analyze images of biological tissue rely on the segmentation of structures as a preliminary step. In particular, laboratories studying the rat brain delineate brain regions to position scientific findings on a brain atlas to propose hypotheses about the rat brain and, ultimately, the human brain. Our work intersects with the preliminary step of delineating regions in images of brain tissue via computational methods.

We investigate pixel-wise classification or segmentation of brain regions using ten histological images of brain tissue sections stained for Nissl substance. We present a deep learning approach that uses the fully convolutional neural network, U-Net, …

Decision Making Under Uncertainty With A Special Emphasis On Geosciences And Education, Laxman Bokati

Open Access Theses & Dissertations

In many practical situations, we need to make a decision. In engineering, we need to decideon the best design of a system, and, for existing systems - on the best control strategy. In financial applications, we need to decide what is the best way to invest money. In geosciences, we need to decide whether we should explore a possible mineral deposit - or whether we should perform more experiments and measurements (and what exactly). In some cases, we can compute the exact consequences of each decision - e.g., if we are controlling a satellite. However, in many other cases, we …

A Central Compact Hybrid-Variable Method With Spectral-Like Resolution, Md Mahmudul Hasan

Open Access Theses & Dissertations

Numerical methods for hyperbolic conservation laws have been a driving force for theresearch in scientific computing and simulation science in the past decades, as many physical, biological, and engineering systems are governed by these equations, such as fluid mechanics, tumor growth, and virtual wind tunnel simulations. Despite the existence of many schemes in the literature, people have never stopped searching for more accurate and efficient methods for these problems. Indeed, the increasing complexity of systems in emerging applications demands better resolution of sub-grid scale phenomenon whereas classical methods usually fail to deliver high-fidelity simulation results of such systems within realistic …