Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
A Simplified Model For Growth Factor Induced Healing Of Wounds, F. J. Vermolen, E. Van Baaren, J. A. Adam
A Simplified Model For Growth Factor Induced Healing Of Wounds, F. J. Vermolen, E. Van Baaren, J. A. Adam
Mathematics & Statistics Faculty Publications
A mathematical model is developed for the rate of healing of a circular or elliptic wound. In this paper the regeneration, decay and transport of a generic 'growth factor', which induces the healing of the wound, is taken into account. Further, an equation of motion is derived for radial healing of a circular wound. The expressions for the equation of motion and the distribution of the growth factor are related in such a way that no healing occurs if the growth factor concentration at the wound edge is below a threshold value. In this paper we investigate the influence of …
Healing Times For Circular Wounds On Plane And Spherical Bone Surfaces, J. A. Adam
Healing Times For Circular Wounds On Plane And Spherical Bone Surfaces, J. A. Adam
Mathematics & Statistics Faculty Publications
A mathematical model is developed for the rate of healing of a circular wound in a spherical "skull". The motivation for this model is based on experimental studies of the "'critical size defect" (CSD) in animal models; this has been defined as the smallest intraosseous wound that does not heal by bone formation during the lifetime of the animal [1]. For practical purposes, this timescale can usually be taken as one year. In [2], the definition was further extended to a defect which has less than ton percent bony regeneration during the lifetime of the animal. CSDS can "heal" by …