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Full-Text Articles in Physical Sciences and Mathematics

Error Propagation And Algorithmic Design Of Contour Integral Eigensolvers With Applications To Fiber Optics, Benjamin Quanah Parker Dec 2021

Error Propagation And Algorithmic Design Of Contour Integral Eigensolvers With Applications To Fiber Optics, Benjamin Quanah Parker

Dissertations and Theses

In this work, the finite element method and the FEAST eigensolver are used to explore applications in fiber optics. The present interest is in computing eigenfunctions u and propagation constants β satisfing [sic] the Helmholtz equation Δu + k2n2u = β2u. Here, k is the freespace wavenumber and n is a spatially varying coefficient function representing the refractive index of the underlying medium. Such a problem arises when attempting to compute confinement losses in optical fibers that guide laser light. In practice, this requires the computation of functions u referred to as …


From Mdp To Alphazero, David Robert Sewell Nov 2021

From Mdp To Alphazero, David Robert Sewell

Dissertations and Theses

In this paper I will explain the AlphaGo family of algorithms starting from first principles and requiring little previous knowledge from the reader. The focus will be upon one of the more recent versions AlphaZero but I hope to explain the core principles that allowed these algorithms to be so successful. I will generally refer to AlphaZero as theses [sic] core set of principles and will make it clear when I am referring to a specific algorithm of the AlphaGo family. AlphaZero in short combines Monte Carlo Tree Search (MCTS) with Deep learning and self-play. We will see how these …


A New Mathematical Theory For The Dynamics Of Large Tumor Populations, A Potential Mechanism For Cancer Dormancy & Recurrence And Experimental Observation Of Melanoma Progression In Zebrafish, Adeyinka A. Lesi Jan 2021

A New Mathematical Theory For The Dynamics Of Large Tumor Populations, A Potential Mechanism For Cancer Dormancy & Recurrence And Experimental Observation Of Melanoma Progression In Zebrafish, Adeyinka A. Lesi

Dissertations and Theses

Cancer, a family of over a hundred disease varieties, results in 600,000 deaths in the U.S. alone. Yet, improvements in imaging technology to detect disease earlier, pharmaceutical developments to shrink or eliminate tumors, and modeling of biological interactions to guide treatment have prevented millions of deaths. Cancer patients with initially similar disease can experience vastly different outcomes, including sustained recovery, refractory disease or, remarkably, recurrence years after apparently successful treatment. The current understanding of such recurrences is that they depend on the random occurrence of critical mutations. Clearly, these biological changes appear to be sufficient for recurrence, but are they …