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Full-Text Articles in Physical Sciences and Mathematics
The Role Of Mathematical Modeling In Designing And Evaluating Antimicrobial Stewardship Programs, Lester Caudill, Joanna R. Wares
The Role Of Mathematical Modeling In Designing And Evaluating Antimicrobial Stewardship Programs, Lester Caudill, Joanna R. Wares
Department of Math & Statistics Faculty Publications
Antimicrobial agent effectiveness continues to be threatened by the rise and spread of pathogen strains that exhibit drug resistance. This challenge is most acute in healthcare facilities where the well-established connection between resistance and sub-optimal antimicrobial use has prompted the creation of antimicrobial stewardship programs (ASPs). Mathematical models offer tremendous potential for serving as an alternative to controlled human experimentation for assessing the effectiveness of ASPs. Models can simulate controlled randomized experiments between groups of virtual patients, some treated with the ASP measure under investigation, and some without. By removing the limitations inherent in human experimentation, including health risks, study …
The Role Of Mathematical Modeling In Designing And Evaluating Antimicrobial Stewardship Programs, Lester Caudill, Joanna R. Wares
The Role Of Mathematical Modeling In Designing And Evaluating Antimicrobial Stewardship Programs, Lester Caudill, Joanna R. Wares
Department of Math & Statistics Faculty Publications
Antimicrobial agent effectiveness continues to be threatened by the rise and spread of pathogen strains that exhibit drug resistance. This challenge is most acute in healthcare facilities where the well-established connection between resistance and suboptimal antimicrobial use has prompted the creation of antimicrobial stewardship programs (ASPs). Mathematical models offer tremendous potential for serving as an alternative to controlled human experimentation for assessing the effectiveness of ASPs. Models can simulate controlled randomized experiments between groups of virtual patients, some treated with the ASP measure under investigation, and some without. By removing the limitations inherent in human experimentation, including health risks, study …
On The Flow Of Non-Axisymmetric Perturbations Of Cylinders Via Surface Diffusion, Jeremy Lecrone, Gieri Simonett
On The Flow Of Non-Axisymmetric Perturbations Of Cylinders Via Surface Diffusion, Jeremy Lecrone, Gieri Simonett
Department of Math & Statistics Faculty Publications
We study the surface diffusion flow acting on a class of general (non--axisymmetric) perturbations of cylinders Cr in IR3. Using tools from parabolic theory on uniformly regular manifolds, and maximal regularity, we establish existence and uniqueness of solutions to surface diffusion flow starting from (spatially--unbounded) surfaces defined over Cr via scalar height functions which are uniformly bounded away from the central cylindrical axis. Additionally, we show that Cr is normally stable with respect to 2π--axially--periodic perturbations if the radius r>1,and unstable if 0