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Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

Applied Mathematics

Montclair State University

Theses/Dissertations

2021

Articles 1 - 2 of 2

Full-Text Articles in Physical Sciences and Mathematics

Computational Analysis To Study The Efficiency Of Shear Activated Nano-Therapeutics In The Treatment Of Atherosclerosis, Nicholas Jefopoulos Aug 2021

Computational Analysis To Study The Efficiency Of Shear Activated Nano-Therapeutics In The Treatment Of Atherosclerosis, Nicholas Jefopoulos

Theses, Dissertations and Culminating Projects

Strokes are the fifth leading cause of death in the United States and can cause long-term disabilities in patients who survive a stroke. The vast majority of these strokes are ischemic, primarily caused by intracranial atherosclerosis. Most therapies to combat intracranial atherosclerosis simply manage it and do not remove the buildup of plaque. Targeted shear-activated nanotherapeutics are currently being developed to remove these plaques. We discuss the roles that aggregate particle density, aggregate particle diameter, vessel geometry, stenosis shape and breakup threshold play in the efficiency of this new technology. Computational studies were performed to test these parameters in three …


Extinction Of Species Due To Deterministic And Stochastic Interactions In Food Webs, Claire M. Burke May 2021

Extinction Of Species Due To Deterministic And Stochastic Interactions In Food Webs, Claire M. Burke

Theses, Dissertations and Culminating Projects

Previous research on the extinctions that occur in niche model food webs with deterministic and stochastic dynamics has shown that the structure of the food web can play an important role in extinction cascades. In this thesis, other types of synthetic food web models are considered, namely the cascade and generalized cascade models, and the extinction cascades of these food webs are compared with previous findings on the extinction cascades from the niche model. It was found that there are many similarities in the results for all three models, which prompted a closer analysis using food webs with deterministic dynamics. …