Physical Sciences and Mathematics Commons^™

Bifurcations And Stability In Models Of Infectious Diseases, Bernard S. Chan

Electronic Thesis and Dissertation Repository

This work is concerned with bifurcation and stability in models related to various aspects of infections diseases.

First, we study the dynamics of a mathematical model on primary and secondary cytotoxic T-lymphocyte responses to viral infections by Wodarz et al. This model has three equilibria and the stability criteria of them are discussed. We analytically show that periodic solutions may arise from the third equilibrium via Hopf bifurcation. Numerical simulations of the model agree with the theoretical results. These dynamical behaviours occur within biologically realistic parameter range.

After studying the single-strain model, we analyze the bifurcation dynamics of an …