Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
The Effect Of Surface Curvature On Wound Healing In Bone, J. A. Adam
The Effect Of Surface Curvature On Wound Healing In Bone, J. A. Adam
Mathematics & Statistics Faculty Publications
The time-independent nonhomogeneous diffusion equation is solved for the equilibrium distribution of wound-induced growth factor over a hemispherical surface. The growth factor is produced at the inner edge of a circular wound and stimulates healing in regions where the concentration exceeds a certain threshold value. An implicit analytic criterion is derived for complete healing of the wound. (C) 2001 Elsevier Science Ltd. All rights reserved.
Healing Times For Circular Wounds On Plane And Spherical Bone Surfaces, J. A. Adam
Healing Times For Circular Wounds On Plane And Spherical Bone Surfaces, J. A. Adam
Mathematics & Statistics Faculty Publications
A mathematical model is developed for the rate of healing of a circular wound in a spherical "skull". The motivation for this model is based on experimental studies of the "'critical size defect" (CSD) in animal models; this has been defined as the smallest intraosseous wound that does not heal by bone formation during the lifetime of the animal [1]. For practical purposes, this timescale can usually be taken as one year. In [2], the definition was further extended to a defect which has less than ton percent bony regeneration during the lifetime of the animal. CSDS can "heal" by …