Physical Sciences and Mathematics Commons^™

The Implications Of Content Analysis For The Interpretation Of Unguentaria In Museum Collections, Jenna L. Mortensen

Theses and Dissertations

Scent has traditionally been an ephemeral component of rituals in ancient societies, including burial and other practices associated with the anointing of the body (Classen et al. 1994: 43; Houston and Taube 2000: 271). This thesis investigates the possible signifiers and social impact such scents might have had for individuals participating in such rituals by using the little explored approach of sensory archaeology. A discussion of the correlation between olfaction and the triggering of both the experiential and emotional aspects of memory contributes to a broader view of these rituals in the anthropological literature (Classen et al. 1994), while Houston …

Extraction Of Indicator Dyes Into Imidazolium-Based Ionic Liquids, Sarah Oplawski

Theses and Dissertations

Among the major classes of water pollutants, dyestuffs have proven to be particularly problematic, both in terms of the quantities released to the environment and the difficulties involved in their recovery from aqueous solution. Each year, textile mills worldwide discharge millions of gallons of dye-laden effluents, leading to significant adverse environmental impact as a consequence of the high chemical oxygen demand and toxicity of these effluent streams. For this reason, there has been considerable interest in the development of a means by which to remove dyes from aqueous waste streams. To accomplish this, textile mills generally employ a combination of …

Quantitative Mass Spectrometric Investigations Of Protein Biomarkers: Serum Thymidine Kinase 1 And Human Osteopontin, Morse Faria

Theses and Dissertations

Mass spectrometry is being increasingly used in biomarker research mainly due to its ability to achieve high selectivity coupled with high sensitivity. This dissertation focuses on quantitative mass spectrometric investigations of two protein biomarkers i.e. serum thymidine kinase 1 (TK1) and human osteopontin (OPN).

First part of this research was focused on developing a liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method for measuring the activity of TK1 in serum by monitoring the conversion of a TK1 specific exogenous substrate, 3’-deoxy-3’-fluorothymidine (FLT), to its mono-phosphorylated form 3’-deoxy-3’-fluorothymidine monophosphate (FLT-MP). A method to quantify FLT-MP on LC-MS/MS was developed and …

Fabrication And Characterization Of High Surface Area Gold Electrodes, Madhura S. Damle

Theses and Dissertations

High surface area gold electrodes are very good substrates for biosensors, catalysis and drug delivery. Their performance is characterized by good sensitivity, low detection limit and high signal. As a result, extensive research is being carried out in this field using different approaches of fabrication to generate high surface area porous electrodes of different morphology, pore size and structure. The morphology of the electrodes can be changed based on whether the approach involves a template or not, types of metal deposition, method and time of dealloying etc. The deposition of metal can be carried out using various approaches such as …

Exploring The Asymmetric Environment Of Various Chiral Catalysts Using A Modified Ion-Trap Mass Spectrometer: Towards The Development Of A Rapid Chiral Catalyst Screening Method, Cary M. Davis

Theses and Dissertations

Since the tragedy of the drug Thalidomide® in the late 1950 to early 1960’s, chirality has been recognized as an important aspect that must be controlled in the drug development process in the pharmaceutical industry. Since then, there has been a considerable movement towards single enantiomer drugs. This demand has presented many challenges for the synthetic organic chemist. Chiral catalysts offer one solution to this problem, as they afford the unique ability to preferentially synthesize one enantiomer. Unfortunately, the design of new chiral catalysts is often empirical, with luck and trial and error necessary due to factors that govern enantioselectivity. …