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Veterinary Toxicology and Pharmacology

Hydrogels

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Full-Text Articles in Veterinary Preventive Medicine, Epidemiology, and Public Health

Release Kinetics Of Methylene Blue In Pluronic F-127 Hydrogel, Meredith Hayden Aug 2019

Release Kinetics Of Methylene Blue In Pluronic F-127 Hydrogel, Meredith Hayden

Animal Science Undergraduate Honors Theses

“Between January 1998 and March 2000, veterinarians at the ASPCA National Animal Poison Control Center (NAPCC) consulted on more than 1,050 cases of accidental exposures to acetaminophen and 1,100 cases of ibuprofen ingestion in dogs and cats” (Richardson, 2000).

NSAID toxicity has become an increasingly common occurrence in small companion animals within the last decade due to widespread usage (Zhou, Boudreau, & Freedman, 2014). Depending on the specific drug, treatment is centered around early decontamination and prevention of kidney and hepatic damage, and methemoglobanemia. Currently, methemoglobanemia is treated with intravenous delivery of methylene blue and less commonly through oral administration. …