Open Access. Powered by Scholars. Published by Universities.®

Veterinary Medicine Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 6 of 6

Full-Text Articles in Veterinary Medicine

Copy Number Variation In The Horse Genome, Sharmila Ghosh, Zhipeng Qu, Pranab J. Das, Erica Fang, Rytis Juras, E. Gus Cothran, Sue Mcdonell, Daniel G. Kenney, Teri L. Lear, David L. Adelson, Bhanu P. Chowdhary, Terje Raudsepp Oct 2014

Copy Number Variation In The Horse Genome, Sharmila Ghosh, Zhipeng Qu, Pranab J. Das, Erica Fang, Rytis Juras, E. Gus Cothran, Sue Mcdonell, Daniel G. Kenney, Teri L. Lear, David L. Adelson, Bhanu P. Chowdhary, Terje Raudsepp

Maxwell H. Gluck Equine Research Center Faculty Publications

We constructed a 400K WG tiling oligoarray for the horse and applied it for the discovery of copy number variations (CNVs) in 38 normal horses of 16 diverse breeds, and the Przewalski horse. Probes on the array represented 18,763 autosomal and X-linked genes, and intergenic, sub-telomeric and chrY sequences. We identified 258 CNV regions (CNVRs) across all autosomes, chrX and chrUn, but not in chrY. CNVs comprised 1.3% of the horse genome with chr12 being most enriched. American Miniature horses had the highest and American Quarter Horses the lowest number of CNVs in relation to Thoroughbred reference. The Przewalski horse …


The Distribution Pattern Of Halicephalobus Gingivalis In A Horse Is Suggestive Of A Haematogenous Spread Of The Nematode, Christina Henneke, Anna Jespersen, Stine Jacobsen, Martin K. Nielsen, Fintan Mcevoy, Henrik E. Jensen Sep 2014

The Distribution Pattern Of Halicephalobus Gingivalis In A Horse Is Suggestive Of A Haematogenous Spread Of The Nematode, Christina Henneke, Anna Jespersen, Stine Jacobsen, Martin K. Nielsen, Fintan Mcevoy, Henrik E. Jensen

Veterinary Science Faculty Publications

The majority of Halicephalobus gingivalis-infections in horses have been fatal and are usually not diagnosed before necropsy. Therefore, knowledge about the nematode and the pathogenesis of infection in horses is limited. This has resulted in an on-going discussion about the port of entry and subsequent dissemination of H. gingivalis within the host. The present case of H. gingivalis-infection in a horse was diagnosed ante mortem. Post mortem findings, the distribution pattern of H. gingivalis nematodes in the brain, a high prevalence of inflammation in close relation to blood vessels, and the presence of the nematode in multiple organs …


Biological Variation Of Thromboelastography Variables In Ten Healthy Female Horses, Jennifer Lee Scruggs May 2014

Biological Variation Of Thromboelastography Variables In Ten Healthy Female Horses, Jennifer Lee Scruggs

Masters Theses

Biological variability (BV) has important applications in laboratory medicine. It can be a source of variation in measured analyte values and provide guidance on reference interval use. BV has three components: between-individual variation (CVg), caused by differences in mean values of a particular analyte among members of a group, within-individual variation (CVi), caused by fluctuations around an individual’s inherent homeostatic set point, and analytical variation (CVa). Thromboelastography (TEG), a type of viscoelastic coagulation analysis, is becoming increasingly common in veterinary referral centers. Despite increased popularity, the optimal method of results interpretation is not clear. While population-based reference intervals (PRI) are …


Relationships Between Equine Management Practices And Intestinal Parasite Infection, Abigail Pagel Jan 2014

Relationships Between Equine Management Practices And Intestinal Parasite Infection, Abigail Pagel

Honors Projects

Parasitology is an important area of veterinary medicine, but the risk factors for high parasite loads are not well-understood. Equine intestinal parasites can cause extensive disease and death. In the current study, the relationship between equine intestinal parasite loads and adherence to veterinary guidelines for equine management practices was studied. Satisfactory adherence to guidelines regarding food, pasture, and flooding management was related to lower parasite loads. Adherence to guidelines regarding deworming, quarantine, bedding, and water did not appear to lower parasite loads. Still, adhering to these guidelines has been shown to improve equine welfare, even if they are not related …


Selected Blood Immunological And Biochemical Parameters In Horses Infected With Cyathostominae Before And After Ivermectin Treatment, Malgorzata Ras Norynska, Rajmund Sokol, Andrzej Krzysztof Siwicki Jan 2014

Selected Blood Immunological And Biochemical Parameters In Horses Infected With Cyathostominae Before And After Ivermectin Treatment, Malgorzata Ras Norynska, Rajmund Sokol, Andrzej Krzysztof Siwicki

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was to identify selected blood immunological and biochemical parameters in horses infected with Cyathostominae before and after treatment with ivermectin. Fecal samples were collected before ivermectin treatment and on days 1, 2, 3, 4, 10, 20, 30, 40, 50, 60, and 75 after drug administration. Blood was sampled on the same days to determine levels of total protein, \gamma-globulin, ceruloplasmin, and lysozyme activity. Eggs and dead parasites were excreted until day 3 postivermectin treatment. The reappearance of eggs was observed in 1 horse on day 50, and on day 75 in the remaining animals. Before …


Characterization Of Ige-Mediated Cutaneous Immediate And Late-Phase Reactions In Non-Allergic Horses, Michelle Woodward Jan 2014

Characterization Of Ige-Mediated Cutaneous Immediate And Late-Phase Reactions In Non-Allergic Horses, Michelle Woodward

LSU Master's Theses

ABSTRACT Objectives – To characterize the response of horse skin following intradermal injection of polyclonal rabbit anti-canine IgE (anti-IgE) and rabbit immunoglobulin G (IgG) in an attempt to develop a model of equine allergic skin disease. Study design - In vivo study. Animals – 10 Adult Thoroughbred horses. Methods –Horses were injected intradermally with one of two different concentrations of anti-IgE and rabbit immunoglobulin G (IgG). Wheal measurements and injection site biopsies were obtained before and 20 min, 6 hr, 24 hr, and 48 hr after injection. Tissue sections were stained with Hematoxylin and Eosin, Luna, and Toluidine Blue. Immunohistochemistry …