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Full-Text Articles in Veterinary Medicine
Reference Values For Erythrocyte And Liver Antioxidant Systems In Healthy Male Mice (Mus Musculus), Ergül Belge Kurutaş, Fi̇gen Doran, Seyhan Vari̇nli̇
Reference Values For Erythrocyte And Liver Antioxidant Systems In Healthy Male Mice (Mus Musculus), Ergül Belge Kurutaş, Fi̇gen Doran, Seyhan Vari̇nli̇
Turkish Journal of Veterinary & Animal Sciences
The aim of the present study was to define the reference values for erythrocyte and liver tissue glucose-6-phosphate dehydrogenase (G6PDH), glutathione peroxidase (GPX), glutathione reductase (GR) and superoxide dismutase (SOD) activities and also reduced glutathione (GSH) levels in order to obtain basal data for subsequent toxicological investigations. In addition, the best storage conditions were determined for liver G6PDH enzyme. Male, apparently healthy Mus musculus (38) speciemens that had normal livers (histopathological data) were included in the study. G6PDH and GPX activities and GSH levels were measured by the Beutler method, and SOD aktivity was measured by the Fridovich method in …
Effects Of Phorbol Myristate Acetate On The Liver: A Biochemical And Ultrastructural Study, Memduha Gülhal Bozkir, Ufuk Ö. Mete, Özkan Oğuz
Effects Of Phorbol Myristate Acetate On The Liver: A Biochemical And Ultrastructural Study, Memduha Gülhal Bozkir, Ufuk Ö. Mete, Özkan Oğuz
Turkish Journal of Veterinary & Animal Sciences
The effects of free radicals in the liver tissue of 20 mice were studied. The mice, separated into acute and chronic groups, were injected with phorbol myristate acetate (PMA) to trigger the release of free radicals. For evaluation of the effects of free radicals, malandialdehyde (MDA) measurement and electron microscopic examination were performed. The results showed that the level of lipid peroxide in the chronic PMA group was significantly higher than it was in the acute PMA group (P