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In Vitro Investigation On Extracellular Traps Formation Of Cat Polymorphonuclearleucocytes Against Toxoplasma Gondii, Nesli̇han Sürsal Şi̇mşek, Ayşe Çakmak, Kader Yildiz
In Vitro Investigation On Extracellular Traps Formation Of Cat Polymorphonuclearleucocytes Against Toxoplasma Gondii, Nesli̇han Sürsal Şi̇mşek, Ayşe Çakmak, Kader Yildiz
Turkish Journal of Veterinary & Animal Sciences
Neutrophil granulocytes are one of the most important defenders of the innate immune system in the host. Moreover, neutrophils are able to reach the inflammation area and kill the pathogens using various defense strategies including neutrophil extracellular traps (NETs). However, there is still not enough information available regarding the innate immunity against Toxoplasma gondii in cats that are both definitive and intermediate hosts of this parasite. Therefore, we investigated the in vitro NETs formation which is induced by cat polymorphonuclear leucocytes (PMNs) against T. gondii tachyzoites. Firstly, PMNs were isolated from cat venous blood samples by using discontinues Percoll dilutions …