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Full-Text Articles in Veterinary Medicine
Acute Encephalopathy And Clinical Pathology Findings In A Sheep With Chronic Copper Poisoning, Nektarios D. Giadinis, Nikolaos Papaioannoy, Maria Kritsepi-Konstantinou, Nikolaos Roubies, Nikolaos Raikos, Harilaos Karatzias
Acute Encephalopathy And Clinical Pathology Findings In A Sheep With Chronic Copper Poisoning, Nektarios D. Giadinis, Nikolaos Papaioannoy, Maria Kritsepi-Konstantinou, Nikolaos Roubies, Nikolaos Raikos, Harilaos Karatzias
Turkish Journal of Veterinary & Animal Sciences
A 3-year-old East Friesian sheep from a sheep flock that suffered from chronic copper poisoning was forwarded to the Clinic of Farm Animals in the Aristotle University. The animal had signs of a hemolytic disease indicative of chronic copper poisoning and also nervous signs. Laboratory examinations were consistent with chronic copper poisoning. This was confirmed after necropsy and liver toxicological analysis. By blood smear examination, metarubricytosis, basophilic stippling, anisocytosis, and polychromasia were found. Also, brain histopathological examination revealed focal areas of gliosis in the cerebral cortex and white matter areas. Satellitosis, neuronal degeneration (chromatolysis) and neuronophagia were also observed. These …