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An Evaluation Of Pathophysiology And Biomechanics Of Selected Lamenesses In The Horse, Cole Barrett Sandow
An Evaluation Of Pathophysiology And Biomechanics Of Selected Lamenesses In The Horse, Cole Barrett Sandow
LSU Master's Theses
INTRODUCTION-Laminitis and synovitis are two common causes of equine lameness. Laminitis is most often associated with hyperinsulinemia and osteoarthritis is most commonly the result of synovitis. The objective is to evaluate biomechanical and pathophysiologic events regarding laminitis and synovitis.
MATERIALS AND METHODS-The first study evaluated biomechanical effects of insulin on lamellar strength. For this experiment, lamellar explants were harvested, incubated in media only (serving as a control) or media with a high concentration of insulin for 8 hours. After incubation, structural integrity was evaluated with a mechanical testing device. Data included load to failure (N), stress to failure (MPa), elongation …