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Full-Text Articles in Veterinary Medicine
The Effects Of Intra-Articular Silicone Polymer On Synovial Fluid, Synovial Tissue, And Articular Cartilage In The Equine Middle Carpal Joint, Marilyn Rumbaugh
The Effects Of Intra-Articular Silicone Polymer On Synovial Fluid, Synovial Tissue, And Articular Cartilage In The Equine Middle Carpal Joint, Marilyn Rumbaugh
LSU Master's Theses
There is anecdotal documentation that intra-articular administration of liquid silicone is used as a lubricant for equine joints. Effects of silicone polymer on equine articular cartilage and synovial fluid have not been evaluated. The objectives were to characterize the effects of intra-articular administration of liquid silicone polymer on clinical, synovial fluid, and microscopic features in normal middle carpal joints of horses, and to determine if silicone migrates to the axillary lymph nodes. Eight adult horses were used in this study. Two mLs of 1,000 centistoke, medical-grade silicone was injected into one randomly selected middle carpal joint. The opposite middle carpal …
Role Of Endothelin In The Pathogenesis Of Acute Laminitis In Horses, Ashley Michelle Stokes
Role Of Endothelin In The Pathogenesis Of Acute Laminitis In Horses, Ashley Michelle Stokes
LSU Doctoral Dissertations
Acute laminitis is a severely debilitating disease of the laminae of the equine digit; however, the mechanism(s) of pathogenesis have yet to be fully elucidated. In physiologic states, the endothelium synthesizes substances, such as nitric oxide (NO; vasodilator) and endothelin-1 (ET-1; profound vasoconstrictor), which play a crucial role in vasomotor regulation. The overall hypothesis is that the initiating factor in the onset of acute laminitis is a disruption in the balance between NO and ET-1, which leads to digital vasoconstriction and subsequent laminar ischemic necrosis. In vitro studies with digital vessels from healthy horses and horses with naturally-acquired laminitis determined …
Equine Immunity To Cyathostome Infections, Marie Alexandra Baudena
Equine Immunity To Cyathostome Infections, Marie Alexandra Baudena
LSU Doctoral Dissertations
To study the protective responses of cyathostome-infected ponies, two challenges were performed employing animals with different histories of exposure to these parasites. The hypothesis developed and to be tested in these experiments was that ponies that had longer exposure to cyathostome contaminated pastures would express acquired resistance to infection. The assumption behind this hypothesis was that helminth-naïve ponies infected with cyathostomes would eliminate the infection using only innate immune responses. Whereas previously exposed ponies would eliminate the infection with acquired immune responses, and these would be more effective in ponies with longer exposure to cyathostomes. Thus, helminth-naïve animals would acquire …