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Full-Text Articles in Veterinary Medicine
Identification And Characterization Of A Relish-Type Nf-Kb, Dvrelish In Dermacentor Variabilis, The American Dog Tick, Victoria Irene Verhoeve
Identification And Characterization Of A Relish-Type Nf-Kb, Dvrelish In Dermacentor Variabilis, The American Dog Tick, Victoria Irene Verhoeve
LSU Doctoral Dissertations
Ticks are important worldwide as vectors of bacteria, viruses, and parasites. Pathogenic and non-pathogenic Spotted fever group (SFG) Rickettsia are maintained and transmitted by ticks with specific hard tick-Rickettsia pairings evident in nature. The pathogenic SFG Rickettsia rickettsii is transmitted by the hard tick Dermacentor variabilis. In response to infection, D. variabilis is known differentially respond to SFG Rickettsia infection. The mechanisms of differential immune induction are currently unknown, and are likely involved in the establishment of specific tick-SFG Rickettsia pairings. It was hypothesized that the level of response by D. variabilis to SFG Rickettsia occurs in a species-specific manner, …
Rickettsia Felis, Transmission Mechanisms Of An Emerging Flea-Borne Rickettsiosis, Lisa Diane Brown
Rickettsia Felis, Transmission Mechanisms Of An Emerging Flea-Borne Rickettsiosis, Lisa Diane Brown
LSU Doctoral Dissertations
Rickettsia felis is an emerging insect-borne rickettsial pathogen and the causative agent of flea-borne spotted fever. First described as a human pathogen from the United States in 1991, R. felis is now identified throughout the world and considered a common cause of fever in Africa. The cosmopolitan distribution of this pathogen is credited to the equally widespread occurrence of cat fleas (Ctenocephalides felis), the primary vector and reservoir of R. felis. Additionally, R. felis has been identified in other hematophagous arthropods (including numerous species of fleas, ticks, mosquitoes, and mites). Most transmission cycles of pathogenic Rickettsia include transovarial and transstadial …
Characterization Of Rickettsial Infection Dynamics Within Dermacentor Variabilis And Amblyomma Maculatum, Emma Kate Harris
Characterization Of Rickettsial Infection Dynamics Within Dermacentor Variabilis And Amblyomma Maculatum, Emma Kate Harris
LSU Doctoral Dissertations
Spotted fever group (SFG) Rickettsia are primarily associated with their reservoir host and vector, the tick. Rickettsial colonization and maintenance within the arthropod is a key component of vector competence and pathogen transmission to the mammalian host. Contemporary detection of novel tick hosts for rickettsial species, combined with an unprecedented rise in human cases of SFG rickettsiosis, necessitates a deeper understanding of tick/Rickettsia interactions. The hypothesis for this work is that if primary tick/Rickettsia pairings do not exist then rickettsial determinants account for primary vector/pathogen relationships. To this end, Dermacentor variabilis and Amblyomma maculatum ticks were exposed to R. rickettsii, …