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Full-Text Articles in Veterinary Medicine
Dynamics Of Bovine Tuberculosis In Wild White-Tailed Deer In Michigan, Graham J. Hickling
Dynamics Of Bovine Tuberculosis In Wild White-Tailed Deer In Michigan, Graham J. Hickling
Michigan Bovine Tuberculosis Bibliography and Database
In mid-2001, the author of this report was invited to undertake an exploratory analysis of Michigan Department of Natural Resources’ data on bovine tuberculosis (TB) infection in wild white-tailed (Odocoileus virginianus) in the northeastern Lower Peninsula of the state. The aims of this analysis were:
• to quantify the geographic spread of tuberculous deer in Michigan;
• to investigate key factors influencing the prevalence of disease in the core of the infected area;
• to interpret the results in light of overseas experience with wildlife TB, with a view to
recommending how current management of the disease might …
Environmental And Farm Management Factors Associated With Tuberculosis On Cattle Farms In Northeastern Michigan, John B. Kaneene, Colleen S. Bruning-Fann, Larry M. Granger, Roseann Miller, Barbara A. Porter-Spalding
Environmental And Farm Management Factors Associated With Tuberculosis On Cattle Farms In Northeastern Michigan, John B. Kaneene, Colleen S. Bruning-Fann, Larry M. Granger, Roseann Miller, Barbara A. Porter-Spalding
Michigan Bovine Tuberculosis Bibliography and Database
Objective—To identify major environmental and farm management factors associated with the occurrence of tuberculosis (TB) on cattle farms in northeastern Michigan.
Design—Case-control study.
Sample Population—17 cattle farms with infected cattle and 51 control farms.
Procedure—Each case farm (laboratory confirmed diagnosis of Mycobacterium bovis infection) was matched with 2 to 4 control farms (negative whole-herd test results within previous 12 months) on the basis of type of farm (dairy or beef) and location. Cattle farm data were collected from in-person interviews and mailed questionnaires. Wildlife TB data were gathered through state wildlife surveillance. Environmental data were gathered …
Susceptibility Of Raccoons (Procyon Lotor) To Infection With Mycobacterium Bovis, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple
Susceptibility Of Raccoons (Procyon Lotor) To Infection With Mycobacterium Bovis, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
Tuberculosis due to Mycobacterium bovis infection is endemic in white-tailed deer (Odocoileus virginianus) in the northeastern portion of the lower Michigan peninsula (USA). Various wild carnivores and omnivores, including raccoons (Procyon lotor), are infected with M. bovis within the endemic area. To investigate the pathogenesis of tuberculosis in raccoons and the likelihood of M. bovis transmission from infected raccoons to other susceptible hosts, we experimentally inoculated raccoons with single oral doses of M. bovis (ranging from 30 to 1.7 x 105 colony forming units [CFU]), five daily oral doses of M. bovis (ranging from 10 …
Lesion Development In White-Tailed Deer (Odocoileus Virginianus) Experimentally Infected With Mycobacterium Bovis, M. V. Palmer, W. R. Waters, D. L. Whipple
Lesion Development In White-Tailed Deer (Odocoileus Virginianus) Experimentally Infected With Mycobacterium Bovis, M. V. Palmer, W. R. Waters, D. L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
The recent discovery of tuberculosis in free-living white-tailed deer in northeastern Michigan underscores the need for increased understanding of the pathogenesis of tuberculosis in wildlife species. To investigate lesion development in white-tailed deer, 32 deer were experimentally infected by intratonsilar instillation of 300 colony-forming units of Mycobacterium bovis. Three deer each were euthanatized and examined at days 15, 28, 42, and 56 after inoculation, and five deer each were euthanatized and examined at days 89, 180, 262, and 328 after inoculation. Microscopic lesions first were seen in the medial retropharyngeal lymph node and lung 28 and 42 days after …
Nitric Oxide Production As An Indication Of Mycobacterium Bovis Infection In White-Tailed Deer (Odocoileus Virginianus), W. R. Waters, M. V. Palmer, R. E. Sacco, D. L. Whipple
Nitric Oxide Production As An Indication Of Mycobacterium Bovis Infection In White-Tailed Deer (Odocoileus Virginianus), W. R. Waters, M. V. Palmer, R. E. Sacco, D. L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
White-tailed deer ( Odocoileus virginianus ) are reservoirs for Mycobacterium bovis in northeast Michigan, USA. Production of nitric oxide (NO) by activated macrophages is a potent mechanism of mycobacterial killing. The capacity of macrophages to produce NO, however, varies among mammalian species. The objective of this study was to determine if mononuclear cells from white-tailed deer produce nitrite as an indication of NO production and, if so, is NO produced in response to stimulation with M. bovis antigens. Supernatants were harvested from adherent peripheral blood mononuclear cell (PBMC) cultures that had been stimulated with either Mannheimia haemolytica lipopolysaccharide (LPS) or …
Mycobacterium Bovis–Infected White-Tailed Deer (Odocoileus Virginianus): Detection Of Immunoglobulin Specific To Crude Mycobacterial Antigens By Elisa, W. Ray Waters, Mitchell V. Palmer, Diana L. Whipple
Mycobacterium Bovis–Infected White-Tailed Deer (Odocoileus Virginianus): Detection Of Immunoglobulin Specific To Crude Mycobacterial Antigens By Elisa, W. Ray Waters, Mitchell V. Palmer, Diana L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
White-tailed deer (Odocoileus virginianus) have recently emerged as a source of Mycobacterium bovis infection for cattle within North America. The objective of this study was to evaluate the antibody response of M. bovis–infected deer to crude mycobacterial antigens. Deer were experimentally inoculated with M. bovis strain 1315 either by intratonsilar instillation or by exposure to M. bovis–infected (i.e., in contact) deer. To determine the time course of the response, including the effects of antigen administration for comparative cervical skin testing, serum was collected periodically and evaluated by enzyme-linked immunosorbent assay (ELISA) for immunoglobulin (i.e., IgG heavy …
Bovine Tuberculosis In Michigan Wildlife And Livestock, Stephen M. Schmitt, Daniel J. O'Brien, Colleen S. Brunning-Fann, Scott D. Fitzgerald
Bovine Tuberculosis In Michigan Wildlife And Livestock, Stephen M. Schmitt, Daniel J. O'Brien, Colleen S. Brunning-Fann, Scott D. Fitzgerald
Michigan Bovine Tuberculosis Bibliography and Database
Since 1994, the state of Michigan has recognized a problem with bovine tuberculosis (TB), caused by Mycobacterium bovis, in wild white-tailed deer from a 12-county area in northeastern Lower Michigan. A total of 65,000 free-ranging deer have been tested, and 340 have been found to be positive for M. bovis. The disease has been found in other wildlife species, and, in 1998, in domestic cattle, where to date 13 beef cattle and 2 dairy cattle herds have been diagnosed with bovine TB. Unfortunately, the situation is unique in that there have never been reports of self-sustaining bovine TB …
Tonsillar Lesions In White-Tailed Deer (Odocoileus Virginianus) Naturally Infected With Mycobacterium Bovis, M. V. Palmer, D. L. Whipple, K. L. Butler, S. D. Fitzgerald, C. S. Bruning-Fann, S. M. Schmitt
Tonsillar Lesions In White-Tailed Deer (Odocoileus Virginianus) Naturally Infected With Mycobacterium Bovis, M. V. Palmer, D. L. Whipple, K. L. Butler, S. D. Fitzgerald, C. S. Bruning-Fann, S. M. Schmitt
Michigan Bovine Tuberculosis Bibliography and Database
In 1994, a free-living white-tailed deer (Odocoileus virginianus) in Michigan was diagnosed with tuberculosis caused by Mycobacterium bovis (Schmitt and others 1997). Subsequent surveys conducted by the Michigan Department of Natural Resources and Michigan State University Animal Health Diagnostic Laboratory identified an epidemic of M bovis infection in free-living white-tailed deer in northeast Michigan (Schmitt and others 1997, O'Brien and others 2001). This represents the first known reservoir of M bovis in free-living wildlife in the USA, and the first known epidemic of tuberculosis in white-tailed deer anywhere in the world.
Milk Containing Mycobacterium Bovis As A Source Of Infection For White-Tailed Deer Fawns (Odocoileus Virginianus), M. V. Palmer, W. R. Waters, D. L. Whipple
Milk Containing Mycobacterium Bovis As A Source Of Infection For White-Tailed Deer Fawns (Odocoileus Virginianus), M. V. Palmer, W. R. Waters, D. L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
Setting:White-tailed deer represent the first wildlife reservoir of Mycobacterium bovis in the United States. The behavior of does with nursing fawns provides several potential mechanisms for disease transmission. Little information exists concerning transmission between doe and fawn, specifically transmammary transmission.
Objective: Determine if fawns can become infected by ingestion of milk replacer containing M. bovis, thus simulating transmission from doe to fawn through contaminated milk.
Design: Seventeen, 21-day-old white-tailed deer fawns were inoculated orally with 2x108 CFU (high dose, n=5), 2.5 x 105 to 2.5 x 106 CFU (medium dose, n=5), and 1x104 CFU (low …