Open Access. Powered by Scholars. Published by Universities.®
- Institution
- Keyword
-
- Animals (1)
- Blue-green algae (1)
- California (1)
- Cattle (1)
- Chromatography, Liquid (1)
-
- Cyanobacteria (1)
- Diagnosis (1)
- Dogs (1)
- EDCs (1)
- Endocrine disruption (1)
- Fresh Water (1)
- Kentucky (1)
- Linear Models (1)
- Microcystins (1)
- Poisoning (1)
- Protein Phosphatase 1 (1)
- Protein phosphatase inhibition assay (1)
- Survey (1)
- Tandem Mass Spectrometry (1)
- Veterinary toxicology (1)
- Wildlife conservation (1)
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Veterinary Medicine
Comparison Of Protein Phosphatase Inhibition Assay With Lc-Ms/Ms For Diagnosis Of Microcystin Toxicosis In Veterinary Cases, Caroline E. Moore, Jeanette Juan, Yanping Lin, Cynthia L. Gaskill, Birgit Puschner
Comparison Of Protein Phosphatase Inhibition Assay With Lc-Ms/Ms For Diagnosis Of Microcystin Toxicosis In Veterinary Cases, Caroline E. Moore, Jeanette Juan, Yanping Lin, Cynthia L. Gaskill, Birgit Puschner
Veterinary Diagnostic Laboratory Faculty Publications
Microcystins are acute hepatotoxins of increasing global concern in drinking and recreational waters and are a major health risk to humans and animals. Produced by cyanobacteria, microcystins inhibit serine/threonine protein phosphatase 1 (PP1). A cost-effective PP1 assay using p-nitrophenyl phosphate was developed to quickly assess water and rumen content samples. Significant inhibition was determined via a linear model, which compared increasing volumes of sample to the log-transformed ratio of the exposed rate over the control rate of PP1 activity. To test the usefulness of this model in diagnostic case investigations, samples from two veterinary cases were tested. In August …
The Impact Of Endocrine-Disrupting Chemicals On Wildlife Conservation, Eda Reed
The Impact Of Endocrine-Disrupting Chemicals On Wildlife Conservation, Eda Reed
Honors Theses
Endocrine-disrupting chemicals (EDCs), such as those from plastics and pesticides, have been hypothesized to affect wildlife populations. According to the U.S. National Institute of Environmental Health Sciences, EDCs ‘are chemicals that may interfere with the body’s endocrine system and produce adverse developmental, reproductive, neurological, and immune effects in both humans and wildlife.’ A growing number of studies suggest wildlife are being exposed to EDCs, but how EDCs affect wildlife health and wildlife conservation is less well-understood. Through scientific literature analysis and a survey of wildlife conservationists and practitioners, this study aims to determine the current state of knowledge and data …