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University of South Carolina

Theses/Dissertations

Morphology

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The Effect Of Radiation On Myofiber Properties In Mouse Skeletal Muscle, Dennis K. Fix Jan 2013

The Effect Of Radiation On Myofiber Properties In Mouse Skeletal Muscle, Dennis K. Fix

Theses and Dissertations

Radiotherapy has been proven as an effective and necessary treatment for cancer. The dose given is dependent on cancer type and location. It has been previously established that skeletal muscle is the most radiation tolerant tissue in the body. With that being said there is a current gap in the literature that is missing the effect of radiation doses on the histological properties of skeletal muscle. The overall purpose of this study is to determine the effect that a single unfractionated dose of 16Gy radiation has on histological properties of myofibers when compared to 4 fractionated doses of 4Gy . …