Rehabilitation and Therapy Commons^™

The Effect Of Patterned Sensory Enhancement On Balance And Ambulation In Persons Diagnosed With Parkinson’S Disease, Brittany Barko

Masters Theses

One rehabilitation protocol effective in delaying the symptoms of Parkinson’s Disease (PD) is Lee Silverman Voice Training BIG (LSVT BIG), comprising pre-gait exercises and gait training. This study seeks to determine if combining Patterned Sensory Enhancement (PSE), a music therapy intervention, with LSVT BIG will improve quality of movement. During physical therapy sessions with three participants, a music therapist adapted the PSE stimuli to support each patient’s motor needs, which were then recorded on CD and sent with patients to exercise with at home. Results showed improved balance and ambulation comparing pre- and post- measures of the BERG balance scale …

Prospective Memory Impairment In Parkinson Disease Without Dementia: Cognitive Mechanisms And Intervention, Erin R. Foster

Arts & Sciences Electronic Theses and Dissertations

Cognitive impairment among non-demented individuals with Parkinson disease (PD) produces significant disability, reduced quality of life, and restricted participation. This dissertation will cover PD-related impairment in prospective memory, or the ability to remember to execute delayed intentions at the appropriate moment in the future. Prospective memory impairment in PD is increasingly recognized as a functionally and clinically relevant problem and viable target for cognitive intervention. To lay the groundwork for the development of effective interventions for prospective memory in PD, this dissertation examines the cognitive mechanisms underlying prospective memory impairment in PD and the potential of training in a targeted …

Selective Generation Of Dopaminergic Precursors From Human Fibroblasts By Direct Lineage Conversion, Miao He

Theses & Dissertations

Transplantation of dopaminergic precursors (DPs) is a promising therapeutic strategy of Parkinson’s disease (PD). However, limited cell source for dopaminergic precursors has become a major obstacle for transplantation therapy. In the first part of the study, we demonstrated that Foxa2 is superior to Lmx1a in inducing dopaminergic neuronal differentiation from induced neural progenitor cells (iNPCs). Based on the results above and some other published results, our group demonstrated that mouse fibroblasts can be reprogrammed into induced dopaminergic precursors (iDPs) through ectopic expression of transcription factors Brn2, Sox2 and Foxa2(1). In the current study, we hypothesized that similar strategy …

The Effects Of Dance Therapy On Voice In Patients With Parkinson's Disease In A Multicultural Population, Ivon N. Ramirez

Theses and Dissertations

Current literature suggests that dance therapy in individuals with Parkinson’s disease shows noticeable improvement in motor functions, for example gait and balance improvement. Additionally, patients with Parkinson’s disease who participate in dance therapy may perceive positive benefits on their quality of life. Therefore, it is believed that increases in core support and improvements in posture, as a result of dance therapy, will have effects on the voice in patients with PD.

This thesis pulls from literature supporting treatment approaches in the field of speech-language pathology for voice patients with Parkinson’s disease. The aim of this study was to evaluate the …