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Rehabilitation and Therapy Commons

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Selected Works

2015

Fragile X

Articles 1 - 4 of 4

Full-Text Articles in Rehabilitation and Therapy

Effects Of Sertraline Treatment For Young Children With Fxs, Andrew Ligsay, Laura Greiss Hess, Sarah Fitzpatrick, Kerrie Lemons Chitwood, Jonathan Polussa, Salpi Siyahian, Randi Hagerman Nov 2015

Effects Of Sertraline Treatment For Young Children With Fxs, Andrew Ligsay, Laura Greiss Hess, Sarah Fitzpatrick, Kerrie Lemons Chitwood, Jonathan Polussa, Salpi Siyahian, Randi Hagerman

Laura Greiss Hess

Selective serotonin reuptake inhibitors (SSRIs) help treat many of the phenotypic manifestations of fragile X syndrome (FXS) including anxiety, sensory processing challenges, and communication and intellectual deficits. However, the efficacy of SSRIs has not been previously studied in children with FXS under five-years-old. The purpose of this study was to elucidate group differences in behavior and developmental outcome measures for young children with FXS when treated with sertraline compared to placebo.


Effects Of Sertraline Treatment For Young Children With Fxs, Laura Greiss Hess, Peter Mundy, Randi Hagerman Nov 2015

Effects Of Sertraline Treatment For Young Children With Fxs, Laura Greiss Hess, Peter Mundy, Randi Hagerman

Laura Greiss Hess

Phenotypic manifestations for young children with fragile X syndrome (FXS) include: anxiety, sensory processing challenges, global language and communication deficits and intellectual and developmental disabilities. Many of these symptoms can be treated with medications, including selective serotonin reuptake inhibitors (SSRIs). However to date a clinical trial has not been conducted for children under five years old. This study investigated the following question: Are there group differences on developmental outcome measures for those children treated with sertraline compared to placebo?


Family Meanings, Contexts And Hopes Within A Clinical Trial, Laura Greis Hess, Cynthia Carter Ching, Randi Hagerman Nov 2015

Family Meanings, Contexts And Hopes Within A Clinical Trial, Laura Greis Hess, Cynthia Carter Ching, Randi Hagerman

Laura Greiss Hess

These qualitative analyses are a component of the clinical trial: “Effects of Sertraline Treatment for Young Children with FXS: Examination of Developmental Outcomes and Family Contexts.” We argue that inclusion of a sociocultural perspective within the context of a clinical trial affords consideration of: A dynamic view of development – simultaneous consideration of biological and sociocultural factors (Vygotsky, 1978). Application of a bioecological framework and consideration of ever changing nested settings and contexts over time (Bronfenbrenner, 2005)


Ot, Slp, At & The Iep…Making Sense Of The Alphabet Soup, Laura Greiss Hess, Kerrie Lemons Chitwood Aug 2015

Ot, Slp, At & The Iep…Making Sense Of The Alphabet Soup, Laura Greiss Hess, Kerrie Lemons Chitwood

Laura Greiss Hess

Creating an IEP – or Individualized Educational Program – can be an incredibly confusing and daunting experience. The “alphabet soup” of acronyms and legalese often increases the anxiety and uneasiness for families. There are often many professionals in the room, some just popping in and out during the meeting, and families can feel isolated and not fully part of the process. One way to offset these feelings is to prepare ahead of time.

We’ve designed this article to be an at-a-glance format, combining our professional expertise and some handy resources. This information is presented via FAQs (more alphabet soup for …