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Full-Text Articles in Rehabilitation and Therapy
Effects And Moderators Of Exercise Medicine On Cardiometabolic Outcomes In Men With Prostate Cancer Previously Or Currently Undergoing Androgen Deprivation Therapy: An Individual Patient Data Meta-Analysis, Pedro Lopez, Robert U. Newton, Dennis R. Taaffe, Kerri Winters-Stone, Laurien M. Buffart, Daniel A. Galvão
Effects And Moderators Of Exercise Medicine On Cardiometabolic Outcomes In Men With Prostate Cancer Previously Or Currently Undergoing Androgen Deprivation Therapy: An Individual Patient Data Meta-Analysis, Pedro Lopez, Robert U. Newton, Dennis R. Taaffe, Kerri Winters-Stone, Laurien M. Buffart, Daniel A. Galvão
Research outputs 2022 to 2026
Purpose: To examine the effects and moderators of exercise effects on cardiometabolic outcomes in men with prostate cancer previously or currently undergoing androgen deprivation therapy (ADT). Results: Seven trials including 560 patients were examined. Exercise resulted in significant effects on whole-body and regional fat mass (P ≤ 0.001). For whole-body fat mass, significant exercise effects were observed in patients who were unmarried (−1.4 kg, P < 0.05) and who presented with higher fat mass levels (−1.0 kg, P < 0.05). For diastolic blood pressure and low-density lipoprotein (LDL), younger (−4.7 mmHg, P < 0.05) and older patients (−0.2 mmol.l-1, P < 0.10) achieved greater effects, respectively. Regarding high-density lipoprotein (HDL), patients undertaking ADT + prostatectomy + radiotherapy derived significant exercise effects (0.3 mmol.l-1, P < 0.05). Conclusions: Exercise effectively reduces fat mass across subgroups of men undergoing or following ADT with different characteristics. For diastolic blood pressure, HDL and LDL, groups based on age and treatment history could be specifically targeted with exercise medicine.
Feasibility Of Supervised Telehealth Exercise For Patients With Advanced Melanoma Receiving Checkpoint Inhibitor Therapy, Brendan J. Crosby, Robert U. Newton, Daniel A. Galvão, Dennis R. Taaffe, Pedro Lopez Da Cruz, Tarek M. Meniawy, Muhammad A. Khattak, Wei-Sen Lam, Elin S. Gray, Favil Singh
Feasibility Of Supervised Telehealth Exercise For Patients With Advanced Melanoma Receiving Checkpoint Inhibitor Therapy, Brendan J. Crosby, Robert U. Newton, Daniel A. Galvão, Dennis R. Taaffe, Pedro Lopez Da Cruz, Tarek M. Meniawy, Muhammad A. Khattak, Wei-Sen Lam, Elin S. Gray, Favil Singh
Research outputs 2022 to 2026
Purpose: To determine the feasibility, safety and preliminary efficacy of a telehealth supervised exercise programme in patients with advanced melanoma receiving checkpoint inhibitor therapy. Methods: A 8-week non-randomised feasibility pilot trial utilising a telehealth delivered multimodal exercise programme undertaken thrice weekly with assessments at baseline and post-intervention. The study was considered feasible if there were no severe or life-threatening adverse events as a result of exercise, and three or more of the following criteria were met: the recruitment rate was > 50%, completion rate was > 80%, median programme attendance was > 75%, median exercise compliance > 75%, and average tolerance was > 70%. Preliminary …