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University of the Pacific

Theses/Dissertations

1969

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Studies On The Localization And Retention Of Tetracycline Hydrochloride In Ehrlich Ascites Cells, Dale William James Jan 1969

Studies On The Localization And Retention Of Tetracycline Hydrochloride In Ehrlich Ascites Cells, Dale William James

University of the Pacific Theses and Dissertations

The antibiotics have become so widely and successfully used in the practice of medicine that they are now considered to be essential. Among the antibiotics, the tetracycline group has achieved an enviable reputation for dependable medication, In spite of this, there remain several unanswered questions, One of these pertains to the interesting phenomenon for almost selective localization of tetracycline in certain tumor cells or masses, Although there have been numerous publications dealing with this phenomenon, as the following paragraphs will indicate, there is little agreement as to the factors involved. Indeed, there are some sharply conflicting opinions.

The investigations described …