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Full-Text Articles in Epidemiology
Cluster Randomized Trials And Statistical Power, Stephen A. Lauer, Nicholas G. Reich
Cluster Randomized Trials And Statistical Power, Stephen A. Lauer, Nicholas G. Reich
Nicholas G Reich
The cluster-randomized trial (CRT) is a common study design in public health research. In situations where dividing a group of individuals into treatment and controls is unethical or impossible, a CRT design maintains the strengths of a randomized study design. By comparing the outcomes of small populations (clusters), we can observe the impacts of interventions on the community as a whole. Public health researchers around the world have utilized CRTs to measure the effect of, for example, de-worming medication on school attendance, financial incentives on doctor absenteeism, and providing chlorine to waterholes. The CRT can be a potent tool, however …