Environmental Public Health Commons^™

Environmental Perspective For System Dynamics Modeling Of Stunting Mitigation To Achieve The Sustainable Development Goals In West Sumatra, Indonesia, Elsa Yuniarti, Nabila Azzahra, Yulhendri Yulhendri, Heldi Heldi, Mery Delvina, Saskia Putri Azeli

Kesmas

This study developed a system dynamics model to simulate stunting reduction in West Sumatra Province, Indonesia, by integrating infant and toddler health, maternal health, and environmental determinants. Secondary data from 2020–2024 on low birth weight, immunization, malnutrition, exclusive breastfeeding, maternal chronic energy deficiency, iron and folic acid supplement distribution, sanitation, and safe drinking water access were compiled from West Sumatra Provincial Health Office and Statistics Indonesia, and validated through consultation with five stakeholder institutions. Causal Loop Diagrams mapped feedback relationships among determinants and were translated into Stock Flow Diagrams using Powersim Studio 10. The model was validated through structural verification, …

Staff Re-Entry Plan — Indian Trail, Flett, Woodridge, Travis Schulhauser

Spokane Wildfire Academic Consortium Repository

Following the downgrade of Level 3 Evacuation orders at Flett Middle School and Indian Trail and Woodridge elementary schools on Aug. 9, district staff worked with Fulcrum Environmental Consulting to conduct visual inspections and air-quality testing at these sites. More than 100 interior and exterior locations were tested, with indoor air quality within the Good-to-Moderate range under the EPA Air Quality Index. Inspectors also found no indication of unusual ash, soot or other settled particulates inside or outside the buildings.

Analysis Of Infectious Waste Management In Hospital X Based On The Minister Of Health Regulation Number 02 Of 2023, Carissa Gianika

Cities and Urban Development Journal

Background: Infectious waste management is a crucial aspect in preventing cross-infection and protecting the hospital environment. Hospitals, as healthcare facilities with high levels of medical activity, generate large amounts of infectious waste that can potentially pose health and environmental risks if not managed according to standards. Hospital X, South Jakarta, as a referral hospital with a high patient volume.

Aims: This study aims to analyze the implementation of infectious waste management at Hospital X, South Jakarta based on the provisions of Minister of Health Regulation Number 2 of 2023, and to identify the obstacles faced in its implementation.

Methods: This …

Clearing The Air: Tracking Spatial And Temporal Pm2.5 Variability Along A Biking Transect In Chicago, Beau R. Rass

DePaul Discoveries

Fine particulate matter (PM₂.₅) poses significant risks to human health and disproportionately affects marginalized communities in urban environments (World Health Organization [WHO], 2021; Tessum et al., 2021). Using low-cost mobile sensors, this study explored spatiotemporal PM₂.₅ concentration patterns along a north–south transect of Halsted Street in Chicago. A 2B Technologies Portable Aerosol Monitor (PAM) mounted on a bicycle was used to continuously record PM₂.₅ concentrations with associated GPS coordinates at approximately two-second intervals during 16 sampling events between 08-12-2025 and 10-05-2025. PM₂.₅ concentrations did not differ significantly among the South Side, West Loop, and North Side regions, contrary to the …

Benefits Of Pet Friendly Work Environments On Physical, Mental, And Social Health Of Office Workers: A Systematic Review, Ahmed Radwan, Jenna Keeman, Tristan Hunzinger, Owen Wilson, Shayla Seymour

People and Animals: The International Journal of Research and Practice

Background: Pet-friendly workplace initiatives are increasingly common, yet the empirical evidence for benefits to office workers’ physical, mental, and social health is scattered and heterogeneous.

Objective: To synthesize evidence on health-related outcomes associated with pet-friendly work environments for office and desk-based workers, and to appraise the current level of evidence.

Methods: A PRISMA-guided systematic search (2014–2024) was conducted in PubMed, PsycINFO, MEDLINE, OVID, CINAHL, and Google Scholar. Two reviewers independently screened titles/abstracts and full texts, extracted data, and appraised study quality using the Critical Appraisal Skills Program (CASP) checklists. Outcomes were coded and synthesized narratively within three domains: physical, mental, …

The Relationship Between Access To Basic Safe Drinking Water And Under-Five Mortality In Indonesia: An Ecological Study, Jasmin Jadevra Fezantino, Raquel Amanda Salmasari, Hanania Carrisa, Zahra Annisaa Hudaya

Jurnal Nasional Kesehatan Lingkungan Global

Infant mortality remains a worrying public health issue, particularly in areas with poor access to drinking water and sanitation. In 2020, Papua Province recorded an infant mortality rate of 49.04 per 1,000 live births and West Papua 47.23. These figures are far above the national average. This study aims to determine the relationship between access to safe drinking water and infant mortality rates in provinces in Indonesia. This study used an ecological design with secondary data from the 2023 Indonesian Health Survey and the 2023 Directorate of Public Health. The analysis was descriptive and followed by a Spearman correlation test. …

Spatial Mapping Of Malaria Cases And Risk Factors Of Its Spread In West Java Province In 2019: An Ecological Study, Nazhira Haliza Putri, Azkia Afiatun Najah Wahyudi, Suhayla Bilqisth Abdi, Mutmainnah Mutmainnah, Nasywan Grananda Rahmantoro, Grace Napitupulu

Jurnal Nasional Kesehatan Lingkungan Global

Malaria is a significant health problem in Indonesia, especially in West Java Province which is at high risk due to its population density and environmental conditions. The incidence of malaria is associated with climate factors (rainfall, humidity, and air temperature). This study aims to study the spatial mapping of malaria cases and their relationship with climate factors. This study used an ecological study design. Secondary data from the West Java Health Office and the West Java Central Statistics Agency in 2019. Univariate and bivariate analysis with the study population covering the entire population of West Java, with a sample of …

Factors Affecting The Incidence Of Stunting In Sawangan Subdistrict, Depok City, In 2023, Amanda Salsabila, Shaumi Maghfira Lamakampali, Erin Shafa Jasmine, Vera Putri Pranoto, Ratu Ayu Dewi Sartika, Primasti Nuryandari Putri

Jurnal Nasional Kesehatan Lingkungan Global

Stunting remains a major problem in Indonesia, particularly in Depok City, West Java. This study aims to analyze the factors influencing stunting in Sawangan District. The study design used is a cross-sectional study, analyzing test variables such as stunting incidence, maternal characteristics (age, education, maternal nutritional status during pregnancy, and personal hygiene), and toddler factors (exclusive breastfeeding status and LBW incidence) using univariate, bivariate (chi-square test), and multivariate (binary logistic regression) analyses. The analysis shows that maternal personal hygiene and LBW incidence in toddlers significantly influence stunting incidence. Other factors, such as age, education, and maternal nutritional status during pregnancy, …

Association Between Cooking Fuel Type And The Incidence Of Acute Respiratory Infections In Toddlers In Indonesia: A Cross-Sectional Study Based On 2017 Sdki Data, Ghina Puspa, Meiravigliosi Hermawan, Nuha Rafida Yumna

Jurnal Nasional Kesehatan Lingkungan Global

Acute Respiratory Tract Infection (ARI) remains a major health problem among toddlers in Indonesia and is closely related to exposure to indoor air pollution. This study aims to analyze the relationship between the type of cooking fuel used by households and the incidence of ARI in toddlers in Indonesia. The study used a cross-sectional design based on data from the 2017 Indonesian Demographic and Health Survey. The study sample included 196,804 respondents who met the inclusion criteria, namely having complete information on the type of cooking fuel and ARI symptoms. The independent variable was the type of cooking fuel divided …

The Relationship Between The Physical Quality Of Household Drinking Water And The Incidence Of Diarrhea In Toddlers In Central Papua Province Based On 2023 Ski Data: A Cross- Sectional Study, Dicky Mahendra Zaglul Zaglul

Jurnal Nasional Kesehatan Lingkungan Global

Diarrhea among children under five remains a significant public health problem, particularly in areas with limited access to clean water, such as Central Papua Province. The physical quality of household drinking water is often used as an initial indicator of water safety; however, its association with diarrhea incidence among under-five children is not yet fully understood. This study aimed to analyze the relationship between the physical quality of household drinking water and the occurrence of diarrhea among children under five in Central Papua Province using data from the 2023 Indonesian Health Survey (SKI). A cross-sectional study design was applied using …

Air Pollution And Public Health: Global Evidence And Implications, Mohammed Obaid Al-Mansoori

Al-Bahir

Globally, the issue of air pollution keep being one of most serious challenges that affecting environment and human health, coming from emissions of industries, transport, agriculture and also from the fuel people use in homes, in addition to natural events that make the situation worse. This review try to bring together the available evidences about the sources, types, and the health impacts of the main air pollutants, including the gaseous ones like SO₂, O₃, NO₂, and CO, and the particulate matter (PM₁₀, PM₂.₅). Exposure for short or long time to these pollutants is linked with many harmful outcomes, such as …

From Combustion Emissions To Neurotoxicity: Brain Health Risks Of Military Burn Pits Exposure, Katherine M. Eggers, Zoe A. Keller, Paul Barach, Julie M. Tomáška, Joshua P. Nixon, Janeen H. Trembley, Tammy A. Butterick

College of Population Health Faculty Papers

Military burn pits used during post-9/11 U.S. military deployments functioned as uncontrolled combustion systems and were widely utilized to dispose of large volumes of outdoor waste by burning. Burn pits involved heterogeneous waste materials burned under variable temperature and oxygen conditions. These combustion environments generated complex, toxic, multipollutant airborne emission mixtures that included particulate matter (PM2.5), polycyclic aromatic hydrocarbons (PAHs), and volatile organic compounds (VOCs). This narrative review synthesizes epidemiologic, experimental, and mechanistic evidence linking burn pit emissions to disruption of the lung–brain axis and adverse neurological outcomes. We specifically aim to address a critical gap in understanding how combustion-derived …

Assessing Indoor Heat Vulnerability And Cooling Strategies In Three Mobile Home Communities In Boulder, Colorado, Usa, Mehdi P. Heris, Skye Niles, Alana Wilson, Megan Mccurdy, Amy Lacourse, Nick Lankau

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Extreme heat is an increasing public health and environmental threat shaped by both physical and social factors. This study assesses the vulnerability of mobile homes and their residents at three mobile home parks in Boulder, Colorado. We examined indoor temperature, housing conditions, and social and personal risk factors of the households. We monitored indoor and outdoor temperatures using 27 indoor and 5 outdoor temperature data loggers, comparing mobile homes with air conditioning, swamp coolers, and passive cooling designs. This work provides a detailed analysis of indoor temperature patterns and demonstrates how evaluating trends yields insights into the performance and effectiveness …

Environmental Contamination Of Methicillin-Resistant Staphylococcus Aureus And Vancomycin-Resistant Enterococcus In Primary Care Clinics: Implications For Occupational Safety, Subki Ahmad, Normah Awang, Ermie Abdull Hamid, Anuar Ithnin, Nurul Farahana Kamaludin, Noraizah Muhd Nor

Kesmas

Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant Enterococcus (VRE) are major contributors to healthcare-associated infection, yet data from primary care clinics remain limited. This study assessed environmental contamination in eight clinics in the Klang Valley, Malaysia, and evaluated associated environmental factors. Samples were collected from environmental surfaces and equipment in Medical Officer and Patient Treatment Rooms, then cultured and tested for antimicrobial susceptibility. Environmental parameters, including temperature, relative humidity, air movement, and room density, were measured. Data were analyzed using Kruskal–Wallis, Mann–Whitney, and multiple linear regression analyses. MRSA was detected on 19.8% of environmental surfaces (patient treatment beds (47.3%) and side …

Projected U.S. Cardiovascular Disease Burden From Heat Exposure For Future Greenhouse Gas Scenarios, Gokul Parmeswaran, Sai Rahul Ponnana, Santosh Kumar Sirasapalli, Niketh Surya, Tong Zhang, Zhuo Chen, Jean-Eudes Dazard, Salil V. Deo, Sanjay Rajagopalan

Faculty Scholarship

Importance: Climate change may reverse decades of improvements in cardiovascular disease (CVD) mortality in the US; however, comprehensive regional projections of heat-related CVD burden in the US are unavailable. Objective: To use the county-level observed (2010-2016) heat-related CVD burden in the US to obtain the projected rates through 2050 according to the mean (shared socioeconomic pathway [SSP] 2-4.5) and high (SSP5-8.5) greenhouse gas (GHG) emission pathways. Design, Setting, and Participants: This cross-sectional ecological analysis used county-level summary data including all counties in the contiguous US from 2010 through 2016 as baseline data with projections to 2030 and 2050 under SSP …

Environmental Mercury Alters Immune Pathways Linked To Autoimmune Risk In Mice Mirroring Humans, Maurgan Lee, Paul Stemmer, Randall Gill, Allen Rosenspire, Anil Aranha, Heather Gibson

Medical Student Research Symposium

Background and Purpose: Mercury is a pervasive environmental contaminant, and human epidemiologic studies have linked chronic low-level exposure to increased autoimmune disease-risk. Dysregulated lymphocyte activation and impaired signaling tolerance are central mechanisms in human autoimmunity. Protein phosphorylation governs lymphocyte differentiation and function, alterations in phosphoproteomic networks may represent a signature of immune disruption. This study evaluates how low dose mercury exposure modifies B and T cell abundance and intracellular signaling patterns in BALB/c and Diversity Outbred (DO) mice.

Methods: BALB/c and DO mice were exposed to low dose HgCl2 in their water for two weeks or provided standard water controls. …

Evaluation Of Two Bioaerosol Sampling And Analysis Methods For The Collection Of Airborne Bacteria And Viruses, Elizabeth Detrick

UNLV Theses, Dissertations, Professional Papers, and Capstones

Bioaerosols, defined as airborne particles of biological origin, include bacteria, fungi, viruses, and their byproducts. They are ubiquitous in both indoor and outdoor environments and can cause respiratory infections, allergic reactions, and toxin-mediated illnesses. Air sampling plays a vital role in bioaerosol monitoring by enabling the collection and analysis of airborne microorganisms to assess exposure risk and inform mitigation strategies. The objective of this study was to determine the relative collection efficiency of two air samplers, the MD8 Airscan, a filtration sampling method, and the SKC BioSampler, an impingement sampling method. Aerosolization tests were conducted in a controlled test chamber …

Quantifying Black Carbon Concentrations In Georgia And Analyzing Associated Public Health Risks, Khloe R. Osborne

Honors Theses

Quantifying Black Carbon Concentrations in Georgia and Analyzing Associated Public Health Risks

One of the most daunting challenges of the industrial world is air pollution. Within this broad spectrum, there is an inhalable particle group named PM2.5, which contains black carbon. Black carbon has evidence that supports the generation and worsening of adverse health impacts, which may include birth complications, cognitive deficits in children, pulmonary aggravation, asthma, cardiovascular issues, neurological degenerative patterns, and cancer risk. This is especially seen in vulnerable populations, like children, elderly, and those who already suffer from weakened health, many of which reside in the southern …

Using Geospatial Analysis To Compare Metropolitan Greenspace And Adolescent Obesity, Rachel Schild, Denyelle Kenyon, Zachary Schild

Scholarship Pathways Program

Using Geospatial Analysis and Machine Learning to Compare Metropolitan Greenspace and Rates of Adolescents with Obesity

 Rachel Schild MD | DenYelle Kenyon PhD

 Introduction: Insufficient outdoor activity, influenced by limited access to exercise-friendly greenspaces, may contribute to increasing childhood obesity rates. However, rigorous evaluation of greenspace quality on a citywide scale is lacking. This study aims to characterize greenspace vegetation types and correlate them with adolescent obesity outcomes, identifying optimal characteristics for promoting health. This data could aid city planners in optimizing greenspace allocation and improving vegetation choices.

Methods: Satellite imagery and municipal data were used to map ten cities, …

Health Outcomes In Heat-Intense Areas In Response To Socioeconomic Status, Victoria Zheng, Chandni Patel, Emily Fried, Jayanth Ambat, Lincoln Opara, Rohan Gupta

Rowan-Virtua Research Day

Background: As ambient temperature rises, regions experiencing extreme heat face serious health concerns. This disproportionately affects lower socioeconomic status (SES) individuals in urban areas. This review examines how these “heat islands” affect the health outcomes for those in different socioeconomic statuses.

Methods: The databases used were PubMed, Embase, and Medline, and were searched with keywords such as “heat islands”, “social inequality”, “SES”, and “health outcomes”. After compiling, articles were screened using the inclusion criteria of ages, gender, peer-reviewed and English-written publications, from any location, social determinants as a primary outcome, and directly compared heat with social determinants of health. Articles …

Rowan-Virtua School Of Osteopathic Medicine’S Planetary Pulse: Charting A Course For Planetary Health Excellence, Hope A. Beyer, Deborah Podolin

Rowan-Virtua Research Day

Objective: Despite international acceptance of climate change as the largest threat towards human health, American osteopathic institutions fall short of their allopathic colleagues in adopting a planetary health curriculum. This study (1) evaluates the desire of Rowan-Virtua School of Osteopathic Medicine (Rowan-Virtua SOM) students to learn about planetary health within their medical education, (2) assesses the current planetary health infrastructure supported by Rowan-Virtua SOM and their parent institution, Rowan University, and (3) proposes an adapted planetary health equity curriculum.

Methods: Medical student interest was gauged by use of a Qualtrics survey modeled off of Dr. Karly Hampshire’s 2020 survey of …

The Quantification Of Fluoride Water Quality And Its Significance On Oral Health, Harleen Kaur Maroak

Electronic Theses, Projects, and Dissertations

Fluoride is a naturally occurring mineral and studies have shown that when added to community water supplies, it effectively reduces dental caries. According to the U.S. Public Health Services (PHS), 0.7mg/L is the optimal fluoride level in drinking water to prevent tooth decay. This study focuses on examining the fluoride levels in water in San Bernardino County (SBC) and Riverside County (RC). Data is collected from recently published articles, databases along with assessing the laboratory water sample (n=45) analysis to determine if the fluoride levels are meeting the optimal standards. In SBC, there are total of 154 water systems with …

The Burden Of Neglect: Examining Environmental And Health Risks At Kiteezi Landfill, Uganda, Rebecca Martha Nantale, Nfn Dangpa Wandji Nana, Bright Agbotui, Maame Yaa Okrah, Emmanuel N. Clottey

Montview Journal of Research & Scholarship

The Kiteezi Landfill, located near Kampala, Uganda, exemplifies the severe environmental and health challenges arising from inadequate urban waste management. Established in 1996, the landfill was designed to handle the city's waste but has been operating beyond its capacity for years. By 2024, it had received between 1,500 and 2,000 tons of solid waste daily, far exceeding its intended limits by more than 200%. This study investigates the environmental and public health impacts of the Kiteezi Landfill in Uganda. The primary research question is: How has inadequate waste management at Kiteezi Landfill contributed to environmental degradation and public health crises? …

Cure Sound Project: Study In Silence?, Quezia Abrao, Deeya Bhadresa, Elisa Castro, Fiona Coulbourne, Carlos Flores, Lizzeth Holguin, Lazarus Maldonado, Jeremy Mares, Andrew Martini, Nicole Matthews, Katherine Montero, Mariana Reyes, Jacob Rodriguez, Julieta Ruiz, Eliana Sanchez, Gabriela Varela

Posters - 2026

Difference in sound levels in study areas across campus can affect students’ ability to work and learn efficiently 1.

According to the WHO, safe sound levels are measured to be around 70dB 2. Some study areas on campus experience sound levels exceeding the safe threshold. Unsafe sound levels are considered to be at or above 85dB 3. These unsafe and excessive noise levels negatively affect a student’s ability to concentrate and work efficiently which correlates to a decrease in class performance, attention deficits, and stress 4.

This study aims to get a base-line measurement of dB levels in common study …

Risk Factors Of Leptospirosis Among Agricultural Workers In Southeast Asia: Literature Review, Ronggo Adi Wibowo, Wawa Najwa Nurzakia, Meirany Sasitha Kirana, Yulia Arthemisia Wijaya, Jasmine Ayumaharani Sekaryudha, Dwi Sarwani Sri Rejeki, Rosita Dwi Jayanti

Jurnal Epidemiologi Kesehatan Indonesia

The agricultural sector is the primary source of livelihood for communities in Southeast Asia; however, these activities increase the risk of exposure to zoonotic diseases, particularly leptospirosis. Southeast Asia is one of the regions with the highest incidence of leptospirosis in the world. This literature review aims to identify risk factors for leptospirosis among agricultural workers in Southeast Asia. The search for research articles utilized three databases (Google Scholar, PubMed, and ScienceDirect) using a descriptive approach based on literature review and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. A total of 9,800 articles were screened for …

Thermal Inequities In Public Parks And Open Spaces In Los Angeles Determined By Remote Sensing, Ashley Agatep, Joshua B. Fisher, Kainani Tacazon, Ambar Rivera, Rossmery Zayas, Reginald Archer, Juan Carlos Ruiz Malagon, Jason A. Douglas

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Urban heat island (UHI) effects are amplified by disparities in community-level cooling infrastructure—such as urban public parks and open spaces (PPOS)—with the most severe impacts occurring in communities that lack sufficient city-wide cooling resources. We found that the underserved community of South Los Angeles, as compared to their neighboring West Los Angeles counterparts, suffers a double burden of inequitable (1) access to and (2) absence of cooling materials and surfaces within these spaces, resulting in significantly hotter temperatures. Identifying these inequities requires high-resolution temporal and spatial mapping of surface temperatures, which has been previously limited. In this community-based participatory research …

Heat And Socioeconomic Deprivation Compound To Drive Coronary Heart Disease In Los Angeles, Shutong Huo, Tessa R. Pulido, Reginald S. Archer, Joshua B. Fisher, Jason A. Douglas

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Background:

Socioeconomic deprivation and environmental heat exposure each increase cardiovascular risk, yet evidence is limited on how these stressors co-occur and jointly shape disease burden within cities. Mapping their overlap can inform equity-oriented planning and needs-based allocation of health and social protection resources.

Methods:

We conducted an ecological geospatial analysis of 2,513 census tracts in Los Angeles County. Adult coronary heart disease (CHD) prevalence was obtained from CDC Population Level Analysis and Community Estimates (2021). Socioeconomic deprivation was measured using the Social Deprivation Index (SDI), and heatwave surface heat hazard was measured using land surface temperature (LST) retrieved from the …

Factors Affecting Irritant Contact Dermatitis Among Horticulture Farmers In Semarang District, Indonesia, Maria Goretti Catur Yuantari, Haikal Haikal, Dewi Susanna

Kesmas

Irritant contact dermatitis is a common condition among farmers, but its underlying causes remain poorly understood. This study aimed to identify factors associated with irritant contact dermatitis among horticulture farmers in Semarang District, Indonesia. A cross-sectional survey was conducted among 427 farmers using a validated, reliable structured questionnaire. The results indicated complaints of dermatitis related to contact with irritants. Data were analyzed using the Chi-square test and logistic regression. Analysis revealed that sex, personal hygiene habits, education level, and the number of pesticide types used were significantly associated with irritant contact dermatitis. Female farmers were less likely to develop irritant …

Investigating Tau Pathology In The Retina And Anterior Segment Structures Of The Eye In A 3-Nitropropionic Acid–Induced Tauopathy Mouse Model, Mohamed Sayed Ahmed Abdel-Kader Qasem

Theses and Dissertations

Background and Objectives: Alzheimer's disease, the most prevalent neurodegenerative disorder in older adults, is characterized by accumulation of hyperphosphorylated tau and amyloid-beta (Aβ) plaques in the central nervous system. Given the retina's shared embryological origin with the brain, its direct neural connectivity via the optic nerve, and similarities in vasculature and age-related degeneration patterns, retinal pathology may serve as an early, non-invasive biomarker for Alzheimer's disease. This study employed 3-nitropropionic acid (3NP) as a pathway-specific tauopathy model driven by mitochondrial dysfunction. The study particularly aimed to investigate whether retinal and corneal tau pathology reflects underlying tau-related neurodegeneration triggered by …

Prephiral Bacterial Infectious Agent Triggers Neuroinflammatory Responses And Neurobehavioral Impairment In Wild-Type Mice, Hadeer Atalah

Theses and Dissertations

Neurodegenerative diseases, including Alzheimer's and Parkinson's, present an increasing global challenge, with chronic neuroinflammation identified as a principal factor alongside genetic, environmental, and infectious influences (Boyd et al., 2022).  Epidemiological data associate bacterial infections with a 40% heightened risk of Parkinson's disease; however, the mechanisms—especially the direct connection between peripheral sepsis and the silent onset of central nervous system pathology absent acute meningitis—are inadequately investigated (Smeyne et al., 2021), particularly concerning common pathogens like Klebsiella pneumoniae in high-burden areas such as Egyptian ICUs, where it constitutes 30% of cases (Alkompoz et al., 2023). This study filled the gap by creating …