Open Access. Powered by Scholars. Published by Universities.®
- Institution
- Keyword
-
- COVID-19 (27)
- Humans (14)
- Depression (10)
- Pandemics (7)
- SARS-CoV-2 (7)
-
- Female (6)
- Anxiety (4)
- Male (4)
- Mental health (4)
- Pandemic (4)
- United States (4)
- Adolescent (3)
- Adult (3)
- Child (3)
- Cross-Sectional Studies (3)
- EQ-5D-5L (3)
- Hospitalization (3)
- Resilience (3)
- Surveys and Questionnaires (3)
- WHO-5 (3)
- Aged (2)
- COVID-19 pandemic (2)
- Covid-19 (2)
- Depressive Disorder, Major (2)
- Ethiopia (2)
- Health-related quality of life (2)
- Medical (2)
- Mental health services (2)
- Pregnancy (2)
- Psychiatry (2)
- Publication
- Publication Type
Articles 31 - 32 of 32
Full-Text Articles in COVID-19
Convergent Evidence For The Antiviral Effects Of Several Fda-Approved Phenothiazine Antipsychotics Against Sars-Cov-2 And Other Coronaviruses, Rodrigo Machado-Vieira, João Quevedo, Lokesh Shahani, Jair C Soares
Convergent Evidence For The Antiviral Effects Of Several Fda-Approved Phenothiazine Antipsychotics Against Sars-Cov-2 And Other Coronaviruses, Rodrigo Machado-Vieira, João Quevedo, Lokesh Shahani, Jair C Soares
Faculty, Staff and Student Publications
No abstract provided.
Covid-19 Risk And Outcomes In Patients With Substance Use Disorders, Quangqiu Wang, David C. Kaelber, Rong Xu
Covid-19 Risk And Outcomes In Patients With Substance Use Disorders, Quangqiu Wang, David C. Kaelber, Rong Xu
Faculty Scholarship
The global pandemic of COVID-19 is colliding with the epidemic of opioid use disorders (OUD) and other substance use disorders (SUD) in the United States (US). Currently, there is limited data on risks, disparity, and outcomes for COVID-19 in individuals suffering from SUD. This is a retrospective case-control study of electronic health records (EHRs) data of 73,099,850 unique patients, of whom 12,030 had a diagnosis of COVID-19. Patients with a recent diagnosis of SUD (within past year) were at significantly increased risk for COVID-19 (adjusted odds ratio or AOR=8.699 [8.411–8.997], P<10−30), an effect that was strongest for individuals with OUD (AOR=10.244 [9.107–11.524], P<10−30), followed by individuals with tobacco use disorder (TUD) (AOR=8.222 ([7.925–8.530], P<10−30). Compared to patients without SUD, patients with SUD had significantly higher prevalence of chronic kidney, liver, lung diseases, cardiovascular diseases, type 2 diabetes, obesity and cancer. Among patients with recent diagnosis of SUD, African Americans had significantly higher risk of COVID-19 than Caucasians (AOR=2.173 [2.01–2.349], P<10−30), with strongest effect for OUD (AOR=4.162 [3.13–5.533], P<10−25). COVID-19 patients with SUD had significantly worse outcomes (death: 9.6%, hospitalization: 41.0%) than general COVID-19 patients (death: 6.6%, hospitalization: 30.1%) and African Americans with COVID-19 and SUD had worse outcomes (death: 13.0%, hospitalization: 50.7%) than Caucasians (death: 8.6%, hospitalization: 35.2%). These findings identify individuals with SUD, especially individuals with OUD and African Americans, as having increased risk for COVID-19 and its adverse outcomes, highlighting the need to screen and treat individuals with SUD as part of the strategy to control the pandemic while ensuring no disparities in access to healthcare support.