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Interactions Of Agricultural Pesticide Use Near Home During Pregnancy And Adverse Childhood Experiences On Adolescent Neurobehavioral Development In The Chamacos Study, Carly Hyland
Public Health and Population Science Faculty Publications and Presentations
Background: Studies have documented independent adverse associations between prenatal and early-life exposure to environmental chemicals and social adversity with child neurodevelopment; however, few have considered these exposures jointly. The objective of this analysis is to examine whether associations of pesticide mixtures and adolescent neurobehavioral development are modified by early-life adversity in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) cohort.
Methods: We used linear mixed effects Bayesian Hierarchical Models (BHM) to examine the joint effect of applications of 11 agricultural pesticides within 1 km of maternal homes during pregnancy and youth-reported Adverse Childhood Experiences (ACEs) …