Open Access. Powered by Scholars. Published by Universities.®
- Institution
Articles 1 - 18 of 18
Full-Text Articles in Clinical Epidemiology
Brazilian Longitudinal Study Of Adult Health (Elsa-Brasil): Objectives And Design., Paulo A. Lotufo
Brazilian Longitudinal Study Of Adult Health (Elsa-Brasil): Objectives And Design., Paulo A. Lotufo
Paulo A Lotufo
The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute relevant information with respect to the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular diseases and diabetes. In this report, the authors delineate the study's objectives, principal methodological features, and timeline. At baseline, ELSA-Brasil enrolled 15,105 civil servants from 5 universities and 1 research institute. The baseline examination (2008-2010) included detailed interviews, clinical and anthropometric examinations, an oral glucose tolerance test, overnight urine collection, a 12-lead resting electrocardiogram, measurement of carotid intima-media thickness, echocardiography, measurement of pulse wave velocity, hepatic ultrasonography, retinal fundus photography, and an …
Chronic Non-Communicable Diseases In Brazil: Priorities For Disease Management And Research, Bruce B. Duncan, Dora Chor, Estela M. Aquino, Isabela M. Bensenor, J.Geraldo Mill, M.Ines Schmidt, Paulo A. Lotufo, Alvaro Vigo, Sandhi M. Barreto
Chronic Non-Communicable Diseases In Brazil: Priorities For Disease Management And Research, Bruce B. Duncan, Dora Chor, Estela M. Aquino, Isabela M. Bensenor, J.Geraldo Mill, M.Ines Schmidt, Paulo A. Lotufo, Alvaro Vigo, Sandhi M. Barreto
Paulo A Lotufo
Chronic Non-Communicable Diseases are the main source of disease burden in Brazil. In 2011, the Brazilian Ministry of Health launched the Strategic Plan of Action for Management of Chronic Non-Communicable Diseases focusing on population-based interventions to manage cardiovascular diseases, diabetes, cancer, and chronic respiratory diseases mainly through fi ghting tobacco use, unhealthy diets, physical inactivity and the harmful use of alcohol. Although a signifi cant number of scientifi c studies on chronic diseases and their risk factors have been undertaken in Brazil, few are of cohort design. In this context, the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a cohort …
Vigilância Em Doença Cerebrovascular [Portuguese], Paulo A. Lotufo
Vigilância Em Doença Cerebrovascular [Portuguese], Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
A Reappraisal Of Stroke Mortality Trends In Brazil (1979 To 2009), Paulo A. Lotufo
A Reappraisal Of Stroke Mortality Trends In Brazil (1979 To 2009), Paulo A. Lotufo
Paulo A Lotufo
Background: Brazil has the highest cerebrovascular death rate in the Western Hemisphere. We investigated temporal trends according to gender and stroke subtypes. Methods: We analysed mortality rates between 1979 and 2009 for different stroke subtypes. Data were stratified by sex and age (35–74 y). The annual percent change (APC) and significant changes in the trends were identified with joinpoint Poisson regression. The average annual percent change (AAPC) for 2005-09 was presented because that period had the best quality of information. Results: After excluding deaths due to stroke sequels, for men, the APCs (95% confidence intervals) were: 1979-84: 0.7 (-0.8 to …
A Stepwise Approach To Stroke Surveillance In Brazil: The Emma (Estudo De Mortalidade E Morbidade Do Acidente Vascular Cerebral) Study, Paulo A. Lotufo
A Stepwise Approach To Stroke Surveillance In Brazil: The Emma (Estudo De Mortalidade E Morbidade Do Acidente Vascular Cerebral) Study, Paulo A. Lotufo
Paulo A Lotufo
Background: Stroke mortality rates in Brazil are the highest in the Americas. Deaths from cerebrovascular disease surpass coronary heart disease. Aim: To verify stroke mortality rates and morbidity in an area of Sa˜o Paulo, Brazil, using the World Health Organization Stepwise Approach to Stroke Surveillance. Methods: We used the World Health Organization Stepwise Approach to Stroke Surveillance structure of stroke surveillance. The hospital-based data comprised fatal and nonfatal stroke (Step 1). We gathered stroke-related mortality data in the community using World Health Organization questionnaires (Step 2). The questionnaire determining stroke prevalence was activated door to door in a family-healthprogramme neighbourhood …
Validation Of A Stroke Symptom Questionnaire For Epidemiological Surveys., Paulo A. Lotufo
Validation Of A Stroke Symptom Questionnaire For Epidemiological Surveys., Paulo A. Lotufo
Paulo A Lotufo
CONTEXT AND OBJECTIVE:Stroke is a relevant issue within public health and requires epidemiological surveillance tools. The aim here was to validate a questionnaire for evaluating individuals with stroke symptoms in the Stroke Morbidity and Mortality Study (Estudo de Mortalidade e Morbidade do Acidente Vascular Cerebral, EMMA), São Paulo, Brazil.DESIGN AND SETTING:This was a cross-sectional study performed among a sample of the inhabitants of Butantã, an area in the western zone of the city of São Paulo.METHODS:For all households in the coverage area of a primary healthcare unit, household members over the age of 35 years answered a stroke symptom questionnaire …
Gender Differences Of Case-Fatality Rate In A Brazilian Stroke Registry, Paulo A. Lotufo
Gender Differences Of Case-Fatality Rate In A Brazilian Stroke Registry, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Characteristics Of Small Areas With A Higher Stroke Mortality, Paulo A. Lotufo
Characteristics Of Small Areas With A Higher Stroke Mortality, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Higher Frequency Of Stroke Deaths On Monday And Saturday, Paulo A. Lotufo
Higher Frequency Of Stroke Deaths On Monday And Saturday, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Social Inequalities And The Decline Of Stroke Mortality In The City Of Sao Paulo, Brazil, Paulo A. Lotufo
Social Inequalities And The Decline Of Stroke Mortality In The City Of Sao Paulo, Brazil, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Stroke Prevalence In A Poor Neighbourhood Of Sao Paulo, Brazil: Applying A Stroke Symptom Questionnaire, Paulo A. Lotufo
Stroke Prevalence In A Poor Neighbourhood Of Sao Paulo, Brazil: Applying A Stroke Symptom Questionnaire, Paulo A. Lotufo
Paulo A Lotufo
Background Brazil has one of the highest stroke mortality rates in the world, these rates are most endemic in the poor. We verified the prevalence of stroke in a deprived neighbourhood in the city of Sa˜ o Paulo, Brazil and compared it with other surveys worldwide. Methods A questionnaire with six questions concerning limb and facial weakness, articulation, sensory disturbances, impaired vision, and past diagnosis of stroke was completed door-to-door in a well-defined area of 15 000 people. Questionnaires were considered positive when a participant answered two or more questions about stroke symptoms or the presence of stroke being confirmed …
Stroke Mortality In Brazil: One Example Of Delayed Epidemiological Cardiovascular Transition, Paulo A. Lotufo
Stroke Mortality In Brazil: One Example Of Delayed Epidemiological Cardiovascular Transition, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Race, Gender And Stroke Subtypes Mortality In Sao Paulo, Brazil., Paulo A. Lotufo
Race, Gender And Stroke Subtypes Mortality In Sao Paulo, Brazil., Paulo A. Lotufo
Paulo A Lotufo
Stroke mortality rates have a discrepant distribution according to socioeconomic variables as social exclusion in Brazil. Recently, data from race has been available from the official health statistics considering five categories: White, Mixed, Black, Asian and Native. We addressed in the city of São Paulo, Brazil, an analysis of cerebrovascular mortality according to race (excluding Asian and Native due to small number of events) and gender during 1999-2001 for people aged 30 to 79 years-old. For all cerebrovascular diseases, age-adjusted mortality rates (x 100,000) for men were higher for Black (150.2), intermediate for Mixed (124.2) and lower for White (104.5) …
Higher Burden Of Hemorrhagic Stroke Among Women An Autopsy-Based Study In São Paulo, Brazil, Paulo A. Lotufo
Higher Burden Of Hemorrhagic Stroke Among Women An Autopsy-Based Study In São Paulo, Brazil, Paulo A. Lotufo
Paulo A Lotufo
The aim of this study was to verify the gender difference in sudden cardiovascular death, mainly comparing brain infarction and hemorrhagic stroke. We analyzed 970 autopsy cases from a total of 3,802 nonviolent deaths (448 considered as sudden deaths, 296 undetermined, and 226 non-sudden deaths) including patients aged 30–69 years. All cardiovascular diseases were responsible for 69% of sudden deaths, and all types of stroke for only 14%. The proportions of sudden death for all cardiovascular diseases, coronary heart disease and ischemic stroke deaths were similar for both sexes. However, sudden deaths due to all types of stroke (women 20.0%; …
Stroke In Brazil: A Neglected Disease, Paulo A. Lotufo
Stroke In Brazil: A Neglected Disease, Paulo A. Lotufo
Paulo A Lotufo
The turning point in the transition from infectious diseases to non-transmittable diseases in Brazil occurred in the 1960s, taking the country as a whole. However, considering the main cities, such as São Paulo and Rio de Janeiro, cerebrovascular disease mortality rates have surpassed the “old cardiovascular diseases” like rheumatic heart disease and syphilitic aortic disease since the end of World War II. Until the end of the 1980s, the burden of stroke mortality observed in the main Brazilian cities was higher than in the United States, Canada and western European countries, and similar to what is observed in Eastern Europe …
Trends Of Stroke Subtypes Mortality In Sao Paulo, Brazil (1996-2003), Paulo A. Lotufo, Isabela M. Bensenor
Trends Of Stroke Subtypes Mortality In Sao Paulo, Brazil (1996-2003), Paulo A. Lotufo, Isabela M. Bensenor
Paulo A Lotufo
The decline of stroke mortality rates has been described in Brazil; however, there is no data about stroke subtypes. We described the changes of stroke mortality rates in the city of Sao Paulo (1996-2003) emphasizing intracerebral hemorrhage and cerebral infarction. We categorized mortality data by gender and 10-year age-strata from 30 to 79 years-old. For men, an annual reduction of all types of stroke (-3.9%), and of stroke subtypes as intracerebral hemorrhage (-3.0%) and cerebral infarction was observ e d (-2.7%) as well as, a decline of ill-defined stroke (-7.4%). For women, a decline was observed for all types of …
Stroke Mortality In Sao Paulo (1997-2003). A Description Using The Tenth Revision Of The International Classification Of Diseases, Paulo A. Lotufo
Stroke Mortality In Sao Paulo (1997-2003). A Description Using The Tenth Revision Of The International Classification Of Diseases, Paulo A. Lotufo
Paulo A Lotufo
Stroke mortality rates are higher in Brazil when compared to other countries. The city of Sao Paulo has a good system of mortality surveillance that allow us to describe the epidemiology of the stroke in the city. Our aim was to describe the stroke mortality pattern by gender and age characterizing the ischemic/hemorrhagic ratio. We categorized mortality data by gender and a 10-year age-strata from 30-39 years-old to 70-79 years-old. To avoid random variations, we calculated the mean of all deaths occurred during the period of 1997 to 2003. Mortality rates were calculated using the population from the Brazilian National …
Smoking And Mortality From Cerebrovascular Disorders In Brazil [Portuguese]L: Comparative Study Of Capital Cities Of Metropolitan Regions, 1988 [Porug, Paulo A. Lotufo
Smoking And Mortality From Cerebrovascular Disorders In Brazil [Portuguese]L: Comparative Study Of Capital Cities Of Metropolitan Regions, 1988 [Porug, Paulo A. Lotufo
Paulo A Lotufo
The role of smoking as risk factor for stroke is controversial. An ecological design study was performed to test the association between stroke mortality and smoking in Brazil. Lung cancer mortality was used as a surrogate for smoking habit.The mortality rate for stroke (ICD-9:430-438) and lung cancer (ICD-9: 162) were determined in the following metropolitan areas: Belém, Recife, Salvador, Belo Horizonte, Rio de Janeiro, São Paulo, Curitiba and Porto Alegre for males and females between 30 years-old and 69 years-old. ANOVA test was used to compare both age-adjusted mortality rates. A negative association by ANOVA was determined between age-adjusted rates …